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An emergency situation and a life threatening condition. Unexpected fever occurring while the client is anesthetized, or occurring even hours after surgery. Can recur up to three days after the initial episode.
What is malignant hyperthermia.
When succinylcholine or anesthetic agents are administered, the susceptible client rapidly develops muscle rigidity, tachycardia and elevated temp (105 degrees F or higher). Skin is warm, mottled and respiratory and metabolic acidosis develops. If not treated promptly, the client may develop cardiac arrhythmias and vascular collapse and may die.
The condition is apparently caused by a defect in the membrane of skeletal muscles. A sudden release of calcium by the sarcoplasmic reticulum into contractile muscles causes a high level of intracellular calcium. This, in turn, increases the metabolic rate of muscle cells, increases O2 consumption, and releases heat.
Immediate measures are taken to lower the body temperature and to correct the metabolic imbalance. The anesthetic is discontinued. Dantrolene (Dantrium) is a muscle relaxant. It is given IV to the patient with malignant hyperthermia to block the release of calcium from the sarcoplasmic reticulum and relax the muscles. Other nursing interventions include use of a hypothermia blanket, ice packs, chilled IV fluids and a cold sponge bath. A foley catheter is usually inserted.
From Broyles: Pharmacological Aspects of Nursing Care 7th edition, Section 3 Chapter 11.