Rat Poison
To DOAC or NOAC
Parenteral Controls
Not Front Effects but Side Effects
I Put My Thang Down, Flip it, and Reverse it
100

The two alternative names for warfarin.

What is Jantoven and Coumadin?

100

These are the brand names for apixaban, rivaroxaban, and edoxaban. 

What is Eliquis, Xarelto, and Savaysa?

100

Generic names for Lovenox and Arixtra. 

What is enoxaparin and fondaparinux?
100

This oral anticoagulant must be dispensed in the manufacture's bottle.

What is Pradaxa?

100

The brand names for andexanet alfa, idarucizumab, and 4 factor PCC.

What is Andexxa, Praxbind, and Kcentra?

200
Clotting factors inhibited by warfarin

What are factors II, VII, IX, and X...and protein C and S?

200

This BBW states you should not use edoxaban if a patient's CrCL is above this value. 

What is 95 ml/min?

200
All anticoagulants cause bleeding. These parenteral anticoagulants may cause hyperkalemia. 

What is heparin and LMWH?

200
Reminder: All anticoagulants cause bleeding as a side effect Which anticoagulant causes GI side effects in up to 40% of patients?

What is dabigatrn?

200

Can idarucizumab be used to reverse bivalirudin? Why or why not?

What is No, and it is a monoclonal antibody designed specifically to bind dabigatran

300

WISN, or warfarin induced ____ _____ is characterized by microclots forming in the capillaries, causing blackening of the skin and high mortality rates. 

What is warfarin induced skin necrosis?

300

For atrial fibrillation, a normal maintenance regimen of apixaban is 5 mg BID. Name the criteria for dose reduction.

What is 2 out of 3 of the following criteria:

Age > or = 80 years of age; weight < or = 60 kg, and Serum creatinine > or = 1.5 mg/dL

300

These parenteral anticoagulants may be used to treat heparin induced thrombocytopenia. 

What is bivalirudin (off label), argatroban (labelled use), and fondaparinux (off label) 

300

This oral anticoagulant may cause/or contribute to the development of osteoporosis with long term use.

What is warfarin?

300

Andexxa can be used to reverse these DOACs. 

What are apixaban, rivaroxaban (both approved uses) and edoxaban (off label)

400
An appropriate bridge with warfarin and enoxaparin includes overlapping therapy for _____ days and this additional criteria. 

How long is 5 days? And what is 2 INRS within range taken 24 hours apart?

400

Name all DOACs which must be taken with food.

Rivaroxaban (dabigatran may be taken with food to reduce GI symptoms) 

400

The correct initial dosing recommendation to treat VTE (venous thromboembolism) with unfractionated heparin and the lab which must be drawn in 6 hours to adjust therapy. 

How much is 80 units/kg bolus followed by 18 units/kg/hr and what is aPTT?

400

If your patient experiences painful purple toes which blanch upon contact he or she may be experiencing ______ caused by the anticoagulant ______

What is purple toe syndrome and warfarin?

400

A patient has an INR of 10 and is without any signs of bleeding. Please specify an appropriate reversal agent, route of administration, and expected onset of action. 

What is phytonadione, where is PO, and how long is 24 hours (some sources say full effects at 48 hours) 

500

Name all strengths of warfarin tablets and corresponding colors

How much is 1 mg (pink), 2 mg (purple), 2.5 mg (green), 3 mg (brown), 4 mg (blue) 5 mg (peaches), 5 mg (teal), 7.5 mg (yellow), and 10 mg (white) 
500

Hold DOACS for _____ hours perioperatively for low-bleeding risk procedures and ____ hours perioperatively for moderate-high bleeding risk procedures (assume normal renal function) 

How long is 24 hours and 48 hours?

500

Many anticoagulants have a BBW to avoid use in patients receiving epidurals due to the risk of epidural hematomas which may cause paralysis. What is the preferred anticoagulant to use in a patient receiving an epidural?

What is unfractionated heparin?

500

All 4 Ts in the 4 T-score used to assess risk of heparin induced thrombocytopenia.

What is thrombocytopenia, timing, thrombosis, and oTher
500

Which clotting factor is used to dose Kcentra? For example, if the dose is 25 units/kg. Which of the 4 clotting factors (listed in units) is used to dose the drug?

What is factor IX?