Pills, Potions & Principles
This is a drug that binds only to specific receptor types.
What are selective drugs?
This is the primary mechanism of action for local anesthetics.
Block Na⁺ channels to prevent action potential transmission
This is how much time it takes for half of the dose to be inactivated or eliminated.
What is half-life?
This is the primary goal of muscle relaxants.
What is normalize skeletal muscle excitability
This is the study of chemical agents that affect living processes
What is pharmacology?
This is the ratio of median toxic dose to median effective dose.
What is the therapeutic index?
This is why balanced anesthesia is typically used for general anesthesia.
What is to provide immobility, amnesia, analgesia, reflex inhibition, & rapid reversibility
This is the drug name that refers to the brand name assigned by a pharmaceutical company.
What is the trade name?
This drug is used for BOTH spasticity and muscle spasms.
What is Diazepam (Valium)?
This is what the drug does to the body or the mechanism of the drug's effect.
What is pharmacodynamics?
This route of administration bypasses the gastrointestinal tract.
What is parenteral?
These are the 2 factors that determine the half‑life and duration of effect of local anesthetics.
What is lipid solubility and blood flow?
This is the term for alternative effects of drugs can be unwanted or wanted and bothersome or not.
What are Adverse Drug Reactions?
This is the mechanism of action of botulinum toxin.
What is decrease acetylcholine (Ach) release?
In pharmacodynamics, these activate receptors.
What are agonists?
For most drugs, elimination follows this type of kinetics.
What are first-order kinetics?
This is an early symptom of Local Anesthetic System Toxicity (LAST).
What is tinnitus?
This term is used to describe using an approved drug for a non-approved purpose.
What is "off-label prescribing"?
This is the 2 places where anti‑spasmatic drugs primarily act.
What are the brainstem and spinal cord?
In pharmacodynamics, these block receptors.
What are antagonists?
These are 2 of the 4 reasons PTs should have knowledge of pharmacology.
What is often PTs are able to determine if a patient is not taking a medication as prescribed, expected pt response, how rehab procedures interact with medication, & to optimize outcomes?
This is 3 of the 6 adverse effects commonly seen with older adults after general anesthesia.
What are HR or BP changes, respiratory depression (hypoxemia), delayed motor responses, confusion/disorientation, hallucinations, & temperature regulation?
This is the primary role of the FDA in drug regulation.
What is testing, approving, and classifying drugs as Rx or OTC?
This is the 2 key points of rehab relevance of muscle relaxers.
What is they are used in combo with rehab to enhance outcomes & rehab professionals should be aware of side effects, especially sedation, weakness, gait changes?
This is how the body absorbs, distributes, and eliminates a drug
What is pharmacokinetics?