Antibiotics 101
Antimicrobial Selection
Side Effects & Precautions
Antifungals & Antivirals
Chemotherapy Agents
100

This type of antibiotic targets a wide variety of bacteria, both Gram-positive and Gram-negative.

What is a broad-spectrum antibiotic?

100

Before prescribing an antibiotic, a provider should always obtain this laboratory test to identify the specific bacterial strain.

What is a culture?

100

A common side effect of tetracyclines, especially in children under 8 years old, is discoloration of this body part.

What are teeth?

100

This antifungal, used for systemic infections, must be infused over several hours due to severe side effects like nephrotoxicity and infusion reactions.

What is Amphotericin B?

100

This chemotherapy agent, also used for autoimmune diseases like rheumatoid arthritis, inhibits folic acid metabolism.

What is methotrexate?

200

This broad-spectrum antibiotic class reduces valproic acids.

What are Carbapenems?

200

This aminoglycoside antibiotic requires careful monitoring of peak and trough levels due to its risk of nephrotoxicity and ototoxicity.

What is gentamicin?

200

Fluoroquinolones carry a severe risk of rupturing this important structure in the lower leg.

What is the Achilles tendon?

200

Patients taking isoniazid for tuberculosis should supplement with this vitamin to prevent peripheral neuropathy.

What is Vitamin B6 (pyridoxine)?

200

Some well-known side effect of chemotherapy.

What are alopecia and bone marrow suppression?

300

This class of antibiotics, known for its "-floxacin" suffix, carries a risk of Achilles tendon rupture and severe photosensitivity.

What are fluoroquinolones?

300

This macrolide antibiotic, often used as an alternative for penicillin-allergic patients, is associated with QT prolongation and a risk of sudden cardiac death.

What is Azithromycin?

300

Vancomycin must be infused slowly to avoid this reaction, which causes rash, flushing, and hypotension.

What is Red Man Syndrome?

300

This antiviral medication is commonly prescribed for herpes simplex and varicella-zoster infections.

What is acyclovir?

300

This chemotherapy agent can cause severe cardiotoxicity, leading to heart failure.

What is doxorubicin?

400

This antibiotic combination, often used for pneumocystis pneumonia and UTIs, can cause hyperkalemia and severe skin reactions like Stevens-Johnson Syndrome.

What is trimethoprim-sulfamethoxazole (Bactrim)?

400

In treating a patient with a severe penicillin allergy, a provider may avoid prescribing this related class of antibiotics.

What are cephalosporins?

400

Patients taking aminoglycosides like gentamicin should be closely monitored for damage to these two organs.

What are the kidneys and ears (nephrotoxicity & ototoxicity)?

400

This antifungal class works by disrupting fungal cell membranes.

What are -azoles? 

400

This chemotherapy drug can cause severe bone marrow suppression and is used to treat sickle cell anemia in addition to cancer.

What is hydroxyurea?

500

This tetracycline antibiotic should not be taken with dairy products, antacids, or iron supplements due to decreased absorption.

Bonus: Patient Admin for this drug

What is doxycycline?

Bonus: Sit up for 30 minutes to prevent esophageal ulceration.

500

This antibiotic, often used for tuberculosis, inhibits mycolic acid synthesis and requires vitamin B6 supplementation to prevent peripheral neuropathy.

What is isoniazid?

500

Sulfonamide antibiotics can cause this rare but life-threatening skin reaction characterized by severe blistering and peeling.

What is Stevens-Johnson Syndrome?

500

Patients taking rifampin for tuberculosis should be warned about this harmless but startling side effect affecting bodily fluids.

What is red-orange discoloration of urine, sweat, and tears?

500

Cyclophosphamide can cause this severe urinary side effect, which presents with blood in the urine.

What is hemorrhagic cystitis?