Powdery Mess
The sieve analysis of a powder is conducted to determine a powder's ______________.
Particle Size
This process creates a solid mass from free flowing powders.
What is Compression?
The process of removing water from a frozen mass at a temperature and pressure below the triple point of water.
What is Freeze Drying, or Lyophilization?
What is HPLC?
This control document numerically defines a product's acceptance criteria for specific tests
What is Specification?
This test is conducted to evaluate how a powder will condense when particles are forced to move in a graduated cylinder.
What is Tapped Density?
This piece of equipment is used to combine powders (e.g. active and excipients).
As a young, curious scientist, Dr. Clark had a lab "incident" when he attempted to freeze dry which common beverage?
What is Coffee?
This is the typical assay/drug content range allowed for product release in the US.
What is 90-110%
This control document describes the formula and manufacutring procedure of a pharmaceutical product
What is Master Production Record?
The term commonly used for pure drug.
What is API?
This tablet test measures a tablet's tensile strength in units of Kilopond.
What is Hardness?
This is the primary advantage of lyophilization of a pharmaceutical product
What is Removal of Water?
In HPLC, this fluid is allowed to flow through the analytical column (stationary phase), carrying the compound of interest with it
What is the Mobile Phase?
This control document describes the exact procedure of how to conduct the analysis on a product
What are Test Methods?
This unit operation can be conducted both "wet" and "dry", and is intended to increase particle size of fine powders to improve flow.
What is Granulation?
The weight of tablet is adjusted by changing the depth of the ____________ tablet punch.
What is Lower?
After free water is removed from a freeze-dried product, this step is used to remove bound water
What is Secondary Drying?
This is the law of physics that allows an analyst to convert the absorbance of a solution with its concentration.
What is Beer's Law?
This procedure provides very strict control over any changes to be made to a control document
What is Control of Change?
This test measures the angle that a powder heap forms with a surface and is a surragate indicator of a powder's flow properties.
What is Angle of Repose?
The hardness of the tablet is adjusted by changing the depth of the _____________ tablet punch.
What is Upper?
At the triple point, water exists in equilibrium in these three states: __________, ____________, and ____________.
What are Solid, Liquid, and Gas?
In typical HPLC, this characteristic of the stationary phase allows for the solute to be separated from the mobile phase
What is Hydrophobicity/lipophilicity?
This section of the Common Technical Document describes the Chemistry, Manufacturing, and Controls of a drug product
What is Module 3?