Principles of Drug Administration
What is a primary nursing assessment prior to administering oral medication
ability to swallow
A nurse is caring for a client who is to receive liquid medications via a gastrostomy tube. The client is prescribed phenytoin 250 mg. The amount available is phenytoin oral solution 25 mg/5 mL. How many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
What is 5O mls
Which route of medication is usually absorbed the fastest?
What is IV
The movement of a drug from its site of administration into the bloodstream.
What is Absorption
The time required for the drug to elicit a therapeutic response is described by this phrase.
What is onset
What medication is used to treat anaphylactic reaction?
What is Epinephrine
What is a safety priority intervention for a patient who is receiving an intravenous opioid?
What is respiratory assessment and what is anything related to Fall risk
A nurse is preparing to administer amoxicillin 350 mg PO. Available is amoxicillin 250 mg/5 mL. How many mL should the nurse administer? (Round to the nearest whole number.)
7mls
Where are drugs metabolized
What is the Liver
A measure of the extent of drug absorption for a given drug and route.
What is Bioavailability
The length of time that the drug concentration is sufficient to elicit a therapeutic response is described by this phrase.
What is "duration of action"
What medication reverse the effects of warfarin
What is Vitamin K
A nurse is preparing to administer a topical medication. What is the priority nursing intervention?
Assess the patients skin where the medication will be applied
A nurse is preparing to administer gabapentin 900 mg PO once daily for a client who has neuropathic pain. The amount available is gabapentin 300 mg/capsule. How many capsules should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
3 capsules
A client prescribed a loading dose to be followed by a lower maintenance dose asks the nurse why the maintenance dose is lower. Which response should the nurse provide the client?
Giving a larger dose initially will reduce the chance of side effects.
Term describing transport of drug by the bloodstream to its site of action.
What is distribution
What is bioavailability
the amount of drug available for distribution after the first pass through the liver
Which medication reverses the action of an opioid agonist and most opioid agonist-antagonist medications
What is Naloxone
Where should a nurse administer a buccal medication
In between the cheek and gum
A nurse is preparing to administer desipramine 150 mg PO daily to a client to treat diabetic neuropathy. The amount available is desipramine 100 mg/tablet. How many tablets should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
1.5 mg tablets
The primary organ responsible for drug elimination.
What are the kidneys
The time required for one-half or 50% of a given drug to be removed from the body.
What is half life
What is pharmacokinetics or what the body does to the drug?
ADME: Absorption, Distribution, Metabolism, Excretion.
Antidote for Acetaminophen is called by this name.
What is Acetylcysteine
Placement of a sublingual medication
What is under the tongue
A nurse is caring for a client who is postoperative following knee arthroplasty and has a new prescription for enoxaparin 1mg/kg/dose subcutaneous every 12 hr. The client weighs 185 lb. How many mg should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
What is 84.1 mg
The significance of half life is clinically useful for this reason.
When is steady state reached
The time required for a drug to reach its maximum therapeutic response is described by this phrase.
What is "peak effect"
Onset of action, peak effect and duration of action play an important part in determining these levels.
What are peak and trough levels
What medication is a selective competitive antagonist of the gamma-aminobutyric acid (GABA) receptor and is the only available specific antidote for benzodiazepine toxicity?
What is flumazenil
What does the nurse understand about high alert medication?
What is, High alert medications can cause severe harm to the client if not given properly. The nurse must always verify the dose
How does the nurse determine a pediatric dose?
Pediatric medication dosages are based on the child's weight in kilograms (mg/kg)
Define Synergistic effects?
What is, Synergistic effects occur when two drugs administered together interact in such a way that their combined effects are greater than the sum of the effects for each drug given alone (1 + 1 = greater than 2)
What 2 things can change the pharmacokinetics of a drug?
What is weight and age
parenteral administration routes and what do they bypass?
drugs given by routes other than the digestive tract (enteral route).
What should be assessed prior to drug administration?
What is, Assess drug allergies, vital signs, and laboratory results prior to drug administration