Mechanisms
SSRI's increase the availability of what neurotransmitter in the brain
serotonin
This antifungal is known for its "shake and bake" infusion reaction
amphotericin B
Patients takine MAOIs must avoid these foods to prevent a hypertensive crisis
Tyramine-rich foods
This anticholinergic drug is used for motion sickness and comes in a transdermal patch
Scopolamine
Patients taking statins should avoid this juice, which can increase the risk of toxicity
GFJ
This diuretic reduces potassium excretion, making it potassium-sparing
This adverse effect of metoclopramide may worsen existing bowel obstruction
diarrhea
This class of antidepressants requires a 14-day washout period when switching from MAOIs to prevent serotonin syndrome
SSRIs or SNRIs
Donepezil is used to treat mild to moderate symptoms of this neurodegenerative disorder
Alzheimer’s disease
Statins should be taken at this time of day for maximum efficacy
Bedtime or in the evening
This antidepressant inhibits dopamine and norepinephrine reuptake and is also used for smoking cesation
bupropion
What are symptoms of metabolic syndrome caused by second generation antipsychotics?
Weight gain, hyperlipidemia, diabetes
Patients on antidepressants should be closely monitored for this risk, especially early in treatment
Suicidal ideation
This beta blocker is used for hypertension and heart failure but is contraindicating in asthma patients
propranolol (or labetalol)
Patients taking rifampin must be warned about this harmless but startling side effect.
Orange discoloration of body fluids
This lipid-lowering drug class is the first-line treatment for high LDL cholesterol
Statins
What condition requires regular WBC monitoring when a patient is on clonzapine?
Agranulocytosis
A patient is taking spironolactone and lisinopril and has a potassium level of 6.5 mEq/L. What is the priority nursing action?
Hold any further medication and notify the provider
This anti-tubercular drug is used in both latent and active TB but requires pyridoxine (vitamin B6) supplementation
Isoniazid
What is the antidote for neuroleptic malignant syndrome caused by antipsychotics?
Dantrolene
Beta blockers reduce blood pressure by blocking these receptors in the heart
Beta-1 adrenergic receptors
This diuretic is contraindicated in heart failure due to its risk of pulmonary edema
Mannitol
This lipid-level lowering medication can cause flushing, which can be avoided by taking aspirin or NSAIDs 30 minutes prior
niacin (or nicotinic acid)
This anti-tubercular drug is contraindicated in patients with gout due to its effect on uric acid levels.
Pyrazinamide
Name all of the hypertensives safe to use in pregnancy
Hydralazine, Methyldopa, Nifedipine, Labetalol