Pharmacologic Appetite Stimulants

Atypical Antidepressants

100

Tetracyclic antidepressant that has weight gain as a side effect

What is mirtazapine?

200

Antidepressants that are "typical"

What is tricyclic, SSRI, SNRI, monoamine oxidase inhibitors...?

300

The reason that mirtazapine has sedative effects

What is anti-histamine?

400

The MoA of mirtazapine

What is alpha2 antagonist, 5-HT antagonist?

500

Reasons to use atypical antidepressant

What is • Typical antidepressant therapy has not been helpful • Adverse effects of typical antidepressants are intolerable • Side effects of atypical antidepressants have a desired effect (e.g. drowsiness, weight/appetite gain) • As a supplement to “typical” antidepressants to enhance their effects

Munchies

100

Name of the appetite stimulating drug that is also found in marijuana

What is dronabinol

200

Other patient populations that benefit from appetite stimulants

What is HIV pts, cancer pts

300

Orexigenic hormones

What is Neuropeptide Y (NPY) Melanin-concentrating hormone Agouti-related protein (AgRP) Galanin Galanin-like peptide Orexin

R&D

100

Appetite stimulating drug that mimics this hormone

What is ghrelin

Hormonez

100

A synthetic progestin

What is megesterol acetate?

200

A location of the brain very impacted by ghrelin and leptin

What is the hypothalamus?