The study or science of drugs
Pharmacology
Route of delivering medications orally
Enteral
The time required for one half of a given drug to be removed from the body
Half-life
A reactive site on the surface or inside of a cell
Receptor
Therapy that does not eradicate pre-existing problems the patient may have, but will prevent progression of a disease or condition
Maintenance Therapy
How many names to a drug?
3
1) Chemical name - (+/-)-2-(p-isobutylphenyl) propionic acid
2) Generic name - ibuprofen
3) Trade name - Motrin
Route absorbed under the tongue
Sublingual and or buccal
If a drug was 100%(peak) at 0 hours and then is 50% after 8 hours, what would be the next % of drug after another 8 hours (16 hours total)?
25
Substances that catalyze nearly every biochemical reaction in a cell
Enzyme
Therapy that makes the patient as comfortable as possible. Usually used at end of life care.
Palliative Care
The study of what the body does to the drug
What is pharmacokinetics
Fastest route by which a drug can be absorbed
Parental route
The time required for a drug to reach its maximum therapeutic response.
Peak effect
Drug binds to the receptor, there is a response.
Agonist or Antagonist?
Agonist
Therapy based on clinical probabilities
Empiric Therapy
The study of what the drug does to the body
Pharmacodynamics
Transportation of a drug by the bloodstream to its site of action
Distribution
The length of time that the drug concentrations is sufficient (without more doses) to elicit a therapeutic response
Duration of action
Cytochrome P-450
A broad term for any undesirable occurrence involving medications
Adverse Drug event
The study that focuses on the clinical use of drugs to prevent and treat diseases
Pharmacotherapeutics
Another name for biotransformation
Metabolism
Half -life is clinically useful for determining when what will be reached?
Steady state
"Refers to the physiologic state in which the amt of drug removed via elimination (renal clearance) is equal to the amt of drug absorbed with each dose."
Substances that catalyze nearly every biochemical reaction in a cell
Enzyme
Mutagenic effects