Drug Journey(PK)
What does the "A" in ADME stand for in pharmacokinetics?
What is Absorption?
What is the term for the molecule a drug binds to, like a lock and key?
What is a receptor?
What graph shows the relationship between drug dose and effect?
What is a dose-response curve?
What barrier protects the brain from many drugs?
What is the blood-brain barrier?
The study of how the body affects a drug
What is pharmacokinetics (PK)?
After absorption, drugs are primarily distributed by what fluid?
What is blood?
Agonists activate receptors. What do antagonists do?
What is they block or prevent receptor activation
What is the “therapeutic window”?
The range between the minimum effective dose and the toxic dose.
Drugs taken by mouth face enzymes in which digestive organ?
What is the stomach (and intestines)?
The study of how a drug affects the body
What is pharmacodynamics (PD)?
What organ is mainly responsible for drug metabolism?
What is the liver?
What is the term for the strength of a drug's effect at a receptor site?
What is affinity?
what is an inverse agonist?
what is it produces the opposite effect of an agonist?
Why do fat-soluble drugs last longer in the body?
They are stored in fat tissue and released slowly over time.
A drug that produces no effect on its own but blocks other drugs is called a...?
What is an antagonist?
Which organ is the main route of drug excretion?
What is the kidney?
If Drug A is more potent than Drug B, which drug needs a smaller dose to work?
what is Drug A?
If the dose that causes harm overlaps with the dose that helps, is the drug considered safe or risky?
What is risky?
Which patient factor can slow drug metabolism: being a baby or being a teenager?
What is being a baby?
The maximum effect a drug can produce is called...?
What is efficacy?
What is injection? (IV)
What’s the difference between efficacy and potency?
what is efficacy is the maximum effect a drug can produce; potency is the amount of drug needed to produce an effect.
what happens to the efficacy when an antagonist is added
what is no change to the efficacy?
True or False: All drugs can pass through cell membranes easily.
what is false.
The process of a drug spreading throughout the body is called...?
What is distribution?