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Dynamics-kinetics
volatile agents
Local anesthetics
Induction agents
Benzodiazepines
100
cytochrome P450, nonocytochromic P-450, flavin containing monooxygenase enzymes
What are hepatic microsomal enzymes
100
Most closely correlates with recovery from inhaled anesthesia.
What is blood/gas partition coefficient
100
increases duration of local anesthetics by decreasing rate of absorption into vascular.
What is epinephrine
100
main reason for incompatibility of barbiturates with other IV agents.
What is high alkalinity
100
GABA receptor activated by benzodiazepine
What is GABA A
200
Describes what happens during metabolism
What is Biotransformation
200
Agent most likely to initiate coronary steal syndrome
What is isoflurane
200
local noted for oxidizing hemoglobin to methemoglobin
What is prilocaine
200
mechanism for rapid awakening after IV dose of thiopental.
What is rapid redistribution
200
Amnesia noted for inability to recall past events
What is retrograde amnesia
300
In terms of volume of distribution - effect of decreased water solubility
What is increased volume of distribution
300
Considered organs of the vessel rich group (4).
What is brain, heart, liver, kidney
300
chemical structure present in Esters which potentially cause allergic reaction.
What is para-aminobenzoic acid
300
class of induction agent contraindicated with history of porphyria
What is IV barbiturates
300
metabolite of valium with a half-life of 71 hours
What is desmethyldiazepam or nordazepam
400
involved in metabolism of propofol, midazolam, morphine, and tylenol
What is glucuronidation
400
The vessel rich group recieves this percent of the cardiac output.
What is 75%
400
Side effect includes highest incidence of cardiotoxicity.
What is bupivicaine
400
Chemical structure of induction agent is imidazole
What is etomidate
400
Aggression, agitation, hallucinations, following the administration of benzodiazepine.
What is paradoxical reaction
500
causes cells to hyperpolarize, inhibiting neuronal activity
What is GABA receptor activation
500
Agent with propensity for bronchospasm.
What is desflurane
500
The total dose of marcaine when a patient is given 10cc of 0.25%
What is 2.5 mg
500
agent associated with dissociative anesthesia
What is ketamine
500
Benzodizepines largely cleared by the kidneys, less dependent upon liver function (3)
What is lorazepam, oxazepam, and temazepam