Pharmacology: Adverse Effects, Interactions, and Contraindications

Anticholinergic

100

Effect on pupils

Dilation (mydriasis)

200

Effect on bladder

Urinary retention

300

Effect on mouth and throat

Dry mouth

400

Effect on GI

Constipation

500

Effects on lungs

Relax bronchial smooth muscle, reducing airway narrowing (bronchodilation)  

Decrease mucus production and secretion  

Reduce airway inflammation and remodeling

Adverse effectsWhat will you monitor

100

Antihypertensives

Low blood pressure/orthostatic hypotension

200

NSAIDS

GI upset/irritation/bleeding

300

Opioids (name 2 adverse effects)

CNS depression/respiration

Constipation

400

Petechia and bruising may indicate _________

Bleeding

500

Client reports having taken multiple products containing acetaminophen

Liver toxicity

Antidotes 1

100

Opioids

naloxone (Narcan)

200

acetaminophen

acetylcysteine

300

warfarin (Coumadin)

Vitamin K

400

Iron overload

deferoximine

500

neostigmine (cholinergic crises)

atropine

Antidotes 2

100

benzodiazapines

flumazenil (Romazicon)

200

Heparin

Protamine sulfate

300

Digoxin

DigiFab

400

anaphylaxis reaction

epinephrine

500

Vecuronium (non depolorizing neuromuscular blocking agent)

neostigmine

Contraindications

100

Aged cheese, red wine, cured meats 

MAOI

200

St John's Wort

SSRI and SNRI

300

High vitamin K foods

blood thinners

400

Tetracyclines and quinolones (what food contraindication)

Dairy

500

statins (what food to avoid)

grapefruit