The amount of time it takes for the concentration of the drug in the blood to decrease by half.
What is its half-life.
The body is in a constant effort to maintain this... a state of health and stability
What is homeostasis?
Identifies the drug without regard to who is manufacturing and marketing it
What is generic name or non-proprietary name
Involves the 4 processes of absorption, distribution, metabolism, and elimination.
What is pharmacokinetics?
Refers to an increase in the amount of enzyme available for metabolism
Number of half-lives before a drug is considered eliminated from the body
What are 5 to 7 half-lives?
Branch of pharmacology that studies how drugs act on the body
What is pharmacodynamics?
Name under which the manufacturer markets the drug
What is brand name?
The process by which a drug moves from the bloodstream into other body fluids and tissues and ultimately to its sites of action
What is distribution?
Refers to a decrease of enzymes.
What is inhibition?
Number of half-lives that have happened if a drug goes from a concentration of 20mg/dl to 5mg/dl.
What is 2 half-lives?
A drug that triggers the same cellular response as the body’s own chemical messenger
What is an agonist?
Statin drugs treat this condition
What is high cholesterol?
The process by which a drug enters the circulatory system or bloodstream.
What is absorption?
Aa substance that has been converted through metabolism.
What is a metabolite?
How long it takes for a drug with a 20 hour half-life to be considered eliminated from the body.
What is 100-140 hours?
A drug that prevents the body’s own chemical messenger from binding to a receptor site
What is an antagonist?
The study and identification of drugs from natural sources
What is pharmacognosy?
The process of converting drugs to other biochemical compounds and then excreting them
What is metabolism?
The point at which either no greater benefit is seen or toxicities of the drug are greater than its benefits
What is the ceiling effect?
The rate at which a drug is eliminated from the body per unit of time.
What is clearance?
The study of how the body effects a drug
What is pharmacokinetics?
Large protein structures produced by recombinant deoxyribonucleic acid (rDNA) technology
What are bioengineered drugs?
The liver metabolizes drugs through this system of enzymes.
What is cytochrome P450?
The fraction of a dose available to the target tissue
What is bioavailability?