Drug Half-Life
Pharmacology
What's in a name
Pharmacokinetics
Drug Effects
100

The amount of time it takes for the concentration of the drug in the blood to decrease by half.

What is its half-life.


100
  • The body is in a constant effort to maintain this... a state of health and stability

What is homeostasis?

100
  • Identifies the drug without regard to who is manufacturing and marketing it

What is generic name or non-proprietary name

100

Involves the 4 processes of absorption, distribution, metabolism, and elimination.

What is pharmacokinetics?

100

Refers to an increase in the amount of enzyme available for metabolism

What is induction?
200

Number of half-lives before a drug is considered eliminated from the body

What are 5 to 7 half-lives?

200

Branch of pharmacology that studies how drugs act on the body

What is pharmacodynamics?

200
  • Name under which the manufacturer markets the drug

What is brand name?

200
  • The process by which a drug moves from the bloodstream into other body fluids and tissues and ultimately to its sites of action

What is distribution?

200

Refers to a decrease of enzymes.  

What is inhibition?

300

Number of half-lives that have happened if a drug goes from a concentration of 20mg/dl to 5mg/dl.

What is 2 half-lives?

300
  • A drug that triggers the same cellular response as the body’s own chemical messenger 

What is an agonist?

300

Statin drugs treat this condition

What is high cholesterol?

300
  • The process by which a drug enters the circulatory system or bloodstream. 

What is absorption?

300

Aa substance that has been converted through metabolism.

What is a metabolite?

400

How long it takes for a drug with a 20 hour half-life to be considered eliminated from the body.

What is 100-140 hours?

400
  • A drug that prevents the body’s own chemical messenger from binding to a receptor site

What is an antagonist?

400
  • The study and identification of drugs from natural sources

What is pharmacognosy?

400

The process of converting drugs to other biochemical compounds and then excreting them

What is metabolism?

400
  • The point at which either no greater benefit is seen or toxicities of the drug are greater than its benefits 

What is the ceiling effect?

500

The rate at which a drug is eliminated from the body per unit of time.

What is clearance?

500

The study of how the body effects a drug

What is pharmacokinetics?

500
  • Large protein structures produced by recombinant deoxyribonucleic acid (rDNA) technology

What are bioengineered drugs?

500

The liver metabolizes drugs through this system of enzymes.

What is cytochrome P450?

500
  • The fraction of a dose available to the target tissue

What is bioavailability?