Adrenergic Drugs
α₁ antagonists used to treat hypertension and phaeochromocytoma
Phenoxybenzamine, Prazosin, Doxazosin
Acts on nicotinic acetylcholine receptors and is the addictive compound in tobacco.
Nicotine
Blocks norepinephrine reuptake and is a CNS stimulant drug of abuse.
Cocaine
Monoclonal antibody against TNFα for Crohn’s and rheumatoid arthritis
Adalimumab
PDE5 inhibitor maintaining cGMP and promoting vasodilation.
Sildenafil, Tadalafil
β non-selective antagonists for arrhythmia, angina, hypertension.
Propranolol, Alprenolol
Used to treat nicotine addiction by acting as a partial agonist at NAChRs.
Varenicline
Antidepressant that blocks NET and has anticholinergic effects
Imipramine
Growth factor drug that stimulates granulocyte production.
Filgrastim
Ca²⁺ channel blocker for hypertension.
Nifedipine
β₁ selective antagonists used for hypertension and heart failure.
•Metoprolol, Atenolol, Nebivolol
MAChR agonists used to treat glaucoma and Sjögren’s syndrome.
Pilocarpine, Cevimeline
Stimulates NA release and acts as β agonist, used as nasal decongestant.
Ephedrine
: PGE analogs causing uterine contraction and cervical ripening
Alprostadil, Misoprostol, Gemeprost, Dinoprostone
ACE inhibitor for hypertension and heart failure.
Captopril
: β₂ agonist for asthma and premature labor.
Salbutamol
: MAChR antagonist used to treat sinus bradycardia.
Atropine
CNS stimulant that increases NA release and inhibits reuptake
Amphetamine
: Prostaglandin analog used for glaucoma.
Latanoprost
Thiazide diuretic acting on distal Na⁺/Cl⁻ transporter.
•Bendroflumethiazide
β₃ agonist used for overactive bladder.
Mirabegron
MAChR antagonist used to treat Parkinson’s disease involuntary movements
Benztropine
Inhibits tyrosine hydroxylase, used for phaeochromocytoma.
α-Methyl-tyrosine
CysLT receptor antagonist used for asthma treatment.
Zafirlukast
Corticosteroid that suppresses immune overactivation in COVID-19.
Dexamethasone