Drug Class #1
SSRI What is the MOA, Indications, SE/AE, BB Warning?
MOA: inhibit reuptake of seratonin
Indications: Depression/ Anxiety
SE: Weight Gain/ Sexual Dysfunction
BB: risk for suicide
DORA What is the MOA, Indications, SE/AE, BB Warning?
MOA:Blocks Orexin A & B
Indications:Insomnia
First Generation Antipsychotics What is the MOA, Indications, SE/AE, BB Warning?
MOA: blocks dopamine 2 receptors
Indications: schizophrenia
SE: drowsiness, antocholinergenic effects, sexual dysfunstion, orthostatric hypotension
BB: risk for suicide
Lithium What is the MOA, Indications, SE/AE, BB Warning?
MOA: unknown
Indications: BPD
SE: Polyuria
Which drug requires lab monitoring?
Lithium
SNRI What is the MOA, Indications, SE/AE, BB Warning?
MOA: inhibit reuptake of seratonin and norepinephrine
Indications: Depression/ Anxiety / Migraine Prevention
SE: Sexual Dysfunction
BB: risk for suicide
Histamine one receptor antagonist (Antihistamine) What is the MOA, Indications, SE/AE, BB Warning?
MOA: histamine 1 receptor antagonist
Indications: insomnia, nausea in pregnancy
Second Generation Antipsychotics What is the MOA, Indications, SE/AE, BB Warning?
MOA: blocking dopamine 2 and serotonin receptors
Indications: BPD, depression, schizophrenia
SE: Metabolic effects, EPS and orthostatic hypotension
BB: not to be used for dementia related psychosis
Atomoxetine (Straterra) What is the MOA, Indications, SE/AE, BB Warning?
MOA: blocks reuptake of norepinephrine
Indications: ADHD
Which drug class is a controlled substance?
CNS Stimulants, DORA, BZRA
TCA What is the MOA, Indications, SE/AE, BB Warning?
MOA: same as SNRIs
Indications: Depression
Off label uses: fibromyalgia, IBS, migraines, anxiety
SE: Weight Gain/ Sexual Dysfunction
BB: risk for suicide
BZRA What is the MOA, Indications, SE/AE, BB Warning?
MOA: same as benzodiazapines
Indications: Insomnia
SE: Weight Gain/ Sexual Dysfunction
BB: risk for abuse and dependency
Buproprion (Wellbutrin) What is the MOA, Indications, SE/AE, BB Warning?
MOA: unknown
Indications: Depression
SE: risk for seizures, highest with high doses or rapid titration
BB: risk for suicide & neuropsychiatric events
Modafinil (provigil) What is the MOA, Indications, SE/AE, BB Warning?
MOA: impacts sleep-wakefulness cycle, not fully understood
Indications: Daytime fatigue related to narcolepsy
What's a CAM for Insomnia?
Melatonin
MAOI What is the MOA, Indications, SE/AE, BB Warning?
MOA: monoamine oxidase inactivates norepinephrine
Indications: Depression
SE: Orthostatic Hypotension, Hypertension when interacting with tyramine
BB: risk for suicide
Melatonin Receptor Agonist What is the MOA, Indications, SE/AE, BB Warning?
MOA: activates melatonin receptors
Indications: Insomnia
Trazadone (Oleptro) What is the MOA, Indications, SE/AE, BB Warning?
MOA: inhibit reuptake of seratonin
Indications: Depression
Off label: aggression, agitation related to dementia & insomnia
SE: Triple D's
BB: risk for suicide
What's the first line for depression?
SSRI
What drugs are used for acute psychosis?
Haloperidol, Ziprasidone.
CNS stimulants What is the MOA, Indications, SE/AE, BB Warning?
MOA: CNS Stimulants
Indications: ADHD and Narcolepsy
SE: Weight Loss & Insomnia
BB: abuse and dependency
TCA What is the MOA, Indications, SE/AE, BB Warning?
MOA: histamine antagonist for insomnia
Indications: Depression/ Anxiety
Buspirone (Buspar) What is the MOA, Indications, SE/AE, BB Warning?
MOA: unknown
Indications: Anxiety
Off Label: Depression
What drug is used for smoking cessation?
Zyban
Antipsychotics have a high incidence of ... ?
Medical noncompliance