Therapeutics Mastery
Clinical Thinking
Top 200 drugs
Industry basics
Patient Safety
100

This commonly used antibiotic for ear, nose, and throat infections belongs to the macrolide class and inhibits 50S protein synthesis.

 What is Azithromycin ?

100

 A patient on warfarin with a suspected INR of 8.0 but no bleeding should receive this.

What is vitamin K ?

100

This top-selling PPI, used for GERD and peptic ulcer disease, is the S-isomer of Prilosec.

Esomeprazole

100

This field-based role involves building relationships with Key Opinion Leaders (KOLs) to discuss scientific data and respond to off-label inquiries, all without sales targets.

What is a Medical Science Liaison?

100

A prescription for a Schedule III-V drug cannot be filled or refilled more than 6 months after the date of issuance, or refilled more than this many times, whichever comes first.

What is 5 times ?

200

This commonly used antibiotic to treat C. diff is associated with a disulfiram-like reaction when taken with alcohol.

What is Metronidazole ?

200

Patients on this medication, which acts as a CYP3A4 substrate, must avoid grapefruit juice to prevent dangerous serum level increases?

 What are Statins (specifically Atorvastatin, Lovastatin, or Simvastatin)?

200

This brand-name atypical antidepressant is unique because it lacks significant serotonergic activity, primarily affecting dopamine and norepinephrine, and is also marketed as Zyban for smoking cessation.

 What is Bupropion (Wellbutrin)?

200

Professionals in this department are dedicated to post-approval safety, primarily responsible for detecting, assessing, and preventing adverse drug effects.

What is Pharmacovigilance?

200

This, rather than a capital letter, is used to differentiate similar-sounding drug names to prevent errors.

What is Tall Man Lettering?

300

 This is the maximum number of days in a row you should use Afrin (oxymetazoline) nasal spray to avoid rebound congestion.

What is three days ?

300

 A patient on Spironolactone and Lisinopril develops peaked T-waves on an EKG. What is the diagnosis?

What is Hyperkalemia ?

300

This generic bisphosphonate must be taken at least 30 minutes before the first food or drink of the day, and the patient must remain upright to prevent esophageal irritation.

Alendronate(Fosamax)

300

This strategic function ensures a medication is reachable and affordable for patients by securing formulary inclusion and reimbursement through stakeholder engagement.

What is Market Access?

300

 What does the acronym HIPAA stand for?

What is Health Insurance Portability and Accountability Act?

400

 This agent is a neprilysin inhibitor combined with valsartan, which reduces mortality in HFrEF patients.

What is Sacubitril/Valsartan? ( Entresto)

400

This life-threatening condition occurs when metformin accumulates due to renal failure, shifting metabolism to anaerobic glycolysis.

What is Lactic acidosis?

400

 This novel oral anticoagulant (NOAC) is a direct thrombin (Factor IIa) inhibitor, requiring it to be stored in its original container to prevent degradation from humidity.

What is Dabigatran( Pradaxa)

400

These specialists use real-world evidence (RWE) and economic modeling to prove a drug's value for money to payers and insurance companies.

What is HEOR (Health Economics and Outcomes Research)?

400

This amendment to the FD&C Act created the formal distinction between prescription (legend) drugs and over-the-counter (OTC) drugs.

What is Durham Humphrey amendment ?

500

This rapid infusion of this antibiotic can cause histamine release, leading to flushing, pruritus, erythema and rash

What is Vancomycin ?

500

 A patient taking Sertraline and Tramadol presents with rigid muscles, hyperreflexia, and dilated pupils. What is the condition?

What is Serotonin Syndrome?

500

This generic anti-arrhythmic, brand name Pacerone, carries warnings for pulmonary toxicity, hepatotoxicity, and proarrhythmic effects.

What is Amiodarone

500

This is the term for a drug that is intended to treat a rare disease affecting fewer than 200,000 people in the U.S.

What is Orphan Drug?

500

This USP chapter sets practice standards for non-sterile compounding.

What is USP <795>?