Back to Basics
Frequency of needle/dressing changes
What is Q7days or when dressing no longer occlusive or visibly soiled
The trends of labs in a patient experiencing tumor lysis syndrome
What is an increased potassium, uric acid, and phosphorus; and a decreased calcium
Tubes used to collect busulfan PKs
What are sodium heparin tubes
Oral chemotherapy often used in the treatment of sickle cell disease
What is Hydroxyurea?
The ANC of a patient with a WBC of 0.7, bands of 12 and segs of 28.
What is 280
ANC = WBC x (bands+segs) x 10
The steps you need to take when your patient has a first time fever
What is notify physician and obtain orders as needed, notify pharmacy, reconstitute cefepime as needed, obtain blood cultures for all central line access points, and administer Tylenol. All within 30 minutes
The difference between allopurinol and rasburicase.
Allopurinol prevents the build up of uric acid while rasburicase breaks down uric acid that has already accumulated in the body
What is NPO and steroids
The test needed before cisplatin administration.
What is an audiogram?
The range of the volume of PRBCs for a patient that weighs 19 kgs
What is 190 mls - 285 mls
Blood product volume = 10-15ml/kg
The dose of heparin for a patient with a port who weighs under 10 kg
What is 100 units of heparin mixed with 4 ml of NS
The days of induction when MRD is obtained in a newly diagnosed ALL patient
What are days 8 and 29
A patient would receive bridging therapy when
What is prior to the start of transplant prep. A patient is currently MRD negative but there might be a delay in starting the preparatory regimen and the physicians do not want to risk the underlying disease no longer remaining MRD negative. Common bridging treatments include azacitidine and blinatumomab
Medications that need to be administered and avoided during busulfan.
What are keppra (needed for seizure prophylaxis) and Tylenol (to be avoided for at least 24 hours after last dose of busulfan. Tylenol can cause high levels of busulfan and can lead to increased toxicity)
The time HR 42 leucovorin begins when Methotrexate was started at 1530
What is 3 negative VRE samples, one week apart
Treatment of Wilm's tumor include
What is surgery, radiation, and chemotherapy
Graft failure occurs when
A patient has not engrafted by Day +28 following an allo transplant
Supportive measures during ATG/Atgam infusions
What are premeds of Tylenol, Benadryl, Solo-Medrol, and then scheduled throughout infusion; frequent vital signs, possible IV rocephin
The rate of IV prograf for a patient who is to receive 0.6 mg/day
What is 1.25 ml/hr
dose/concentration/hours
0.6/0.02/24
Our units accrediting entities (the full titles, not abbreviations)
Who are Children's Oncology Group (COG) and the Foundation for the Accreditation of Cellular Therapy
Criteria for LPs for a patient who is CNS positive
What is twice weekly LPs with IT chemo until patient has 3 consecutive negative LPs
The signs and symptoms you see when you suspect your patient has VOD
What is increased weight, increased abdominal girth, abnormal coags, platelet consumption, and reversal of flow on the liver ultrasound
The reason steroids are avoided on a patient who is to receive post transplant cyclophosphamide.
The rates of IVIG infusion for a patient that weights 17.5 kgs
0.005x17.5x60 = 5.25
0.01x17.5x60 = 10.5
0.02x17.5x60 = 21
0.04x17.5x60 = 42
0.05x17.5x60 = 52.5