entero virus
say three characteristics of picornavirus.¿
an envelope .positive sense single strand RNA ,capsid protein VP 1-5 , cytoplasmic replication ,
acid stable , survive in GI tract ,RNA dependent RNA polymerase enzyme and protease , they are very small .
what type of genome does poliovirus have¿
Positive sense single stranded RNA
Envelop or not¿
Non em elope
how is the RNA structure ¿
Positive single stranded RNA
What is the main route of transmission of poliovirus"¿
Fecal_Oral
Where does echo viruse first replicate ¿
Oropharynx and intestinal mucosa
How much is the size of picronovirus¿
28_30 nm
Difference between OPV vs IPV¿
OPV: mucosal and systemic immunity
IPV: mainly systemic IgG
Why cannot infect GI tract¿
Destroyed by stomach acid
Where does replication occur in the cell
Cytoplasm
Most common disease caused by echoviruses ¿
Aseptic maningitis
what is the main disease
Common cold
which enzymes replicate viral RNA¿
RNA dependent RNA polymerase enzyme
Why polio virus cause flucid paralysis¿
Damage lower motor neuron