Polymer-based assemblies
The concentration at which surfactants start to form micelles.
What is the CMC?
The basic building block of polymer micelles.
What are amphiphilic block copolymers?
The general term for a spherical assembly where an aqueous void is surrounded by a membrane.
What is a vesicle?
The cross-linking of chains composed of two comonomer units.
What are copolymer hydrogels?
The effect that drives aggregation of nonpolar solvents to maximize entropy of water.
What is the hydrophobic effect?
The aspect that determines the resulting shape of self-assembled amphiphilic block copolymers (that is not present for surfactants).
What is the hydrophilic fraction?
The name of the ideal polymersome morphology.
What is a small unilamellar vesicle?
An interaction between polymer chains that strongly depends on the pH.
What are hydrogen bonding interactions?
The molecular factor that indicates what kind of structure will be formed.
What is the critical packing parameter (CPP)?
The reason it is important to determine the CMC for micelles intended to be used as drug delivery vesicles.
What is the dilution effect during intravenous injection?
The reason why polymersomes are more stable than liposomes.
What is the result of higher MW of the block copolymer compared to lipids?
Water that binds to the polar hydrophilic part in hydrogels.
What is primary bound water?
The structural factor of the surfactant that controls the CMC.
What is the effect of the chain length of the hydrophobic part?
The temperature at which a glassy polymer becomes rubbery.
What is the glass transition temperature (Tg)?
Two important energies involved in the assembly of polymersomes.
What is the bending energy and the line energy?
The temperature where polymers become insoluble.
What is the LCST (The lower critical solution temperature)?
A micelle preparation method that should have low amounts of residual solvent molecules.
What is the solvent evaporation method?
Polymersome mechanism that is more likely to allow for the encapsulation of protein.
What is mechanism 1?