Post
Transcriptional
Mod
Ifications
Final Jeopardy
100
The addition of this sequence occurs after termination of transcription.
What is the poly(A) tail?
100
This modification occurs during eukaryotic transcription.
What is 5' capping of mRNA?
100
This is the process and location by which introns are removed from mRNA.
What is splicing at the splicesosome?
100
This is the loop-like structure that forms prior to intron removal.
What is a lariat?
200
These mRNAs are not processed after transcription because translation begins during transcription.
What are prokaryotic mRNAs?
200
These RNAs are post-transcriptionally modified in both prokaryotes and eukaryotes.
What are rRNAs and tRNAs?
200
This sequence is added to the 3' end of tRNAs.
What is the CCA sequence?
200
These eukaryotic mRNAs do not have poly(A) tails.
What are histone mRNAs?
300
The 5' cap of mRNAs is added by this type of bond.
What is a 5' to 5' triphosphate linkage?
300
Sequences are removed from these locations on tRNA.
What are both ends of the tRNA and an intron from the anticodon loop?
300
These are the two mechanisms for generating different mRNAs from a single hnRNA.
What are alternative cleavage and polyadenylation and alternative splicing?
300
It is estimated that 15% of all genetic diseases are due to problems with this process.
What are mutations that affect splicing?
400
These are the nucleotides that are important in splicing.
What are the GU nucleotides at the 5' splice donor site, the A nucleotide at the branch site, and the AG nucleotides at the 3' splice acceptor site? (I remember it GUAAG)
500
The DNA sequence 3' CATG 5' codes for this RNA sequence.
What is GUAC?