Complete vs Partial mole
Malignant GTD
Management
Adnexal masses
Management
100
This is the karyotype of a complete mole
most commonly 46 XX or 46 XY
100
Persistence of detectable hcg for more than x months is criteria for diagnosing post molar GTD
What is 6 months
100
Patients with moles are managed with this procedure
What is a D&C
100
This is the most important risk factor for ovarian cancer in the general population
What is age
100
Follow up with TVUS in 6 months would be appropriate for any women with these characteristics pertaining to her adnexal mass
What is unilocular, thin-walled, smooth cyst
200
These ovarian enlargements are rarely seen in a patient with a partial mole
Theca Lutein cysts
200
This type of malignant GTD most commonly follows a term pregnancy
What is gestational choriocarcinoma
200
Once GTD is suspected, this is the minimum imaging study that should be obtained
What is a chest x ray
200
This is the imaging study of choice for evaluating ovarian masses
What is TVUS
200
A postmenopausal female with an adnexal mass should have this imaging study if she has not had one within the past 12 months due possible metastasis from this area to the ovary
What is a mammogram
300
This medical complication seen in a complete mole could cause elevated metabolism leading heart palpitations, heat intolerance, irritability among other exaggerated symptoms
What is hyperthyroidism
300
This rare type of malignant GTD is chemo resistant and can occur after any type of pregnancy
Placental site trophoblastic tumor
300
Patients diagnosed with a pregnancy consisting of a mole after a D&C has been performed should be followed with serial hcg levels every "x" weeks while elevated
What is 1-2 weeks
300
This is a serum marker most useful for nonmucinous epithelial cancers
What is CA-125
300
If a pregnant female is diagnosed with an adnexal mass that needs to be removed, the removal should happen during this part of her pregnancy
What is the second trimester
400
This mole pregnancy usually reveals amnion and fetal red blood cells on pathology.
What is a partial mole
400
Patients with GTD with a score less than "x" number, are classified as low risk according to the FIGO scoring system and will most likely respond to a single agent chemotherapy
What is 6
400
This is the preferred treatment regimen for a patient with nonmetastatic GTD
What is weekly methotrexate injections
400
Simple cysts up to this size are almost always benign and can be followed without intervention, even in postmenopausal women
What is 10 cm
400
A female with an adnexal mass should be evaluated by a gyn oncologist if her family history is positive for either of these cancers in a first degree relative
What is breast or ovarian cancer
500
This is the likelihood of post molar malignant disease in a patient diagnosed with a complete mole
6-32 % risk, most commonly around 20%
500
A patient with more than 8 sites of metastases, one site being the brain, and a hcg greater than 100,000 would have a FIGO score of "x" and therefore would be considered high risk
What is 12
500
This is the risk of a second mole in a subsequent pregnancy after completion of chemotherapy for GTD
What is 1-2 %
500
This the lifetime risk of a women developing ovarian cancer
What is 1 in 70
500
During laparoscopic removal of a cyst, this procedure of a normal appearing contralateral ovary is not advised b/c it could adversely affect future fertility
What is a wedge biopsy