35 year old presents with severe depression with episodes of anxiety for nine months that have become so bad he can no longer leave the house and has severe weight loss, hyperpigmentation of exposed skin, and cold intolerance.
Addison's Disease
13 year old with developmental delay, stereotyped behaviors, as well as hyperactive behavior, large anteverted verted ears, and hyperextensible joints and marcoorchidism. What is the diagnosis and mechanism of genetic disorder?
Fragile X Syndrome, CGG trinueclotide repeat disorder
Insomnia secondary to depression will consistently affect REM sleep in what way?
Reduced latency to REM sleep
What antipsychotic is associated with the least amount of weight gain?
Geodon
An important technique or goal of cognitive behavioral therapy is?
Eliciting and testing automatic thoughts
Hyperthyroidism should be ruled out as a part of the differential diagnosis for what psychiatric disorder?
Panic Disorder
Gene expressed differently when inherited from mom or dad?
Genetic imprinting
What sleep stage is the most important in restoring the altar functions that result from prolonged sleep deprivation?
Stage 4, non rapid eye movement
A 45 year old patient on vinal Zine for MDD takes over the counter medication for cold symptoms and develops hypertensive crisis. Which over the counter medication would most likely cause this?
Pseudophedrine
The treatment goal most specific to psychoanalytic psychotherapy is what?
Bringing the unconscious conflict into awareness
Hyperthyroidism should be ruled out as a part of the differential diagnosis for what psychiatric disorder
-appearance of breast tissue
-increase adrenal androgen production
-first menstrual bleed
-appearance of pubic hair
-growth spurt
increase adrenal androgen production
Which method examines the consistency that gene variants are passed from parent to offspring with different families? This is a genetic technique to analyze chromosomes for a disorder.
Linkage Analysis
What neuropeptide is increased in the hypothalamus in narcolepsy?
Orexin A
The FDA requires that generics not be significantly different from parent compounds and what way?
Bioequivalance
A patient with multiple social fears is terrified of public speaking. As the next step in treatment that therapist arranges for the patient to give 15 minute talk to the clinical staff. What is this example of?
Flooding
58 year old with depression and psychomotor retardation on SSRI. What is the recommended treatment augmentation?
liothyronine
Metachromatic leukodystrophy is associated with a gene mutation in which enzyme?
Aryl Sulfatase
Which medication is most effective in the treatment of cataplexy?
Clomipramine, (TCA's secondary to increase norepinephrine)
What characteristic of lithium makes it readily dialyzable?
low molecular weight
The purpose of DBT is to diminish what?
Parasuicidal thoughts
Parasuicide: An apparent attempt at suicide, commonly called a suicidal gesture, in which the aim is not death
Patient presents with irregular asymmetric small (1 to 2mm) pupils which react to accommodation but not light. What is the diagnosis?
Diabetic Autonomic Neuropathy
What CYP450 polymorphism can lead to lower than expected/lower than normal risperidone levels in the blood?
Multiple copies of wild types allelles
A 17 year old with increased sleep duration to 18 hours, lethargy, cognitive slowing, with a normal sleep EEG likely has what dx?
Kline-Levin syndrome
What disturbance seen on EKG is most common for cardiac effects of lithium?
low T waves associated with hypokalemia
Therapeutic technique where the therapist instructs the patient to hold onto a symptom?
Paradoxical intervention
a therapeutic technique in which a client is directed by the therapist to continue undesired symptomatic behavior, and even increase it, to show that the client has voluntary control over it
For example: The client fears failure, so the therapist asks the client to fail at something. A man has problems with procrastina