Endocrine
Genetics
Sleep
Psychopharm
Therapy
100

35 year old presents with severe depression with episodes of anxiety for nine months that have become so bad he can no longer leave the house and has severe weight loss, hyperpigmentation of exposed skin, and cold intolerance.

Addison's Disease

100

13 year old with developmental delay, stereotyped behaviors, as well as hyperactive behavior, large anteverted verted ears, and hyperextensible joints and marcoorchidism. What is the diagnosis and mechanism of genetic disorder?

 Fragile X Syndrome, CGG trinueclotide repeat disorder 

100

Insomnia secondary to depression will consistently affect REM sleep in what way?

Reduced latency to REM sleep

100

What antipsychotic is associated with the least amount of weight gain?

Geodon

100

An important technique or goal of cognitive behavioral therapy is?

Eliciting and testing automatic thoughts

200

Hyperthyroidism should be ruled out as a part of the differential diagnosis for what psychiatric disorder?

Panic Disorder

200

Gene expressed differently when inherited from mom or dad?

Genetic imprinting

200

What sleep stage is the most important in restoring the altar functions that result from prolonged sleep deprivation?

Stage 4, non rapid eye movement

200

A 45 year old patient on vinal Zine for MDD takes over the counter medication for cold symptoms and develops hypertensive crisis. Which over the counter medication would most likely cause this?

Pseudophedrine

200

The treatment goal most specific to psychoanalytic psychotherapy is what?

Bringing the unconscious conflict into awareness

300

Hyperthyroidism should be ruled out as a part of the differential diagnosis for what psychiatric disorder

-appearance of breast tissue

-increase adrenal androgen production

-first menstrual bleed

-appearance of pubic hair

-growth spurt

increase adrenal androgen production

300

Which method examines the consistency that gene variants are passed from parent to offspring with different families? This is a genetic technique to analyze chromosomes for a disorder.

Linkage Analysis

300

What neuropeptide is increased in the hypothalamus in narcolepsy?

Orexin A

300

The FDA requires that generics not be significantly different from parent compounds and what way?

Bioequivalance

300

A patient with multiple social fears is terrified of public speaking. As the next step in treatment that therapist arranges for the patient to give 15 minute talk to the clinical staff. What is this example of?

Flooding

400

58 year old with depression and psychomotor retardation on SSRI. What is the recommended treatment augmentation?

liothyronine

400

Metachromatic leukodystrophy is associated with a gene mutation in which enzyme?

Aryl Sulfatase

400

Which medication is most effective in the treatment of cataplexy?

Clomipramine, (TCA's secondary to increase norepinephrine)

400

What characteristic of lithium makes it readily dialyzable?

low molecular weight

400

The purpose of DBT is to diminish what?

Parasuicidal thoughts

Parasuicide: An apparent attempt at suicide, commonly called a suicidal gesture, in which the aim is not death

500

Patient presents with irregular asymmetric small (1 to 2mm) pupils which react to accommodation but not light. What is the diagnosis?

Diabetic Autonomic Neuropathy

500

What CYP450 polymorphism can lead to lower than expected/lower than normal risperidone levels in the blood?

Multiple copies of wild types allelles

500

A 17 year old with increased sleep duration to 18 hours, lethargy, cognitive slowing, with a normal sleep EEG likely has what dx?

Kline-Levin syndrome

500

What disturbance seen on EKG is most common for cardiac effects of lithium?

low T waves associated with hypokalemia

500

Therapeutic technique where the therapist instructs the patient to hold onto a symptom?

Paradoxical intervention

a therapeutic technique in which a client is directed by the therapist to continue undesired symptomatic behavior, and even increase it, to show that the client has voluntary control over it

For example: The client fears failure, so the therapist asks the client to fail at something. A man has problems with procrastina