Make or break amyloids
The most stable state for a globular protein.
What is the native state?
The shape of the energy landscape describing how a protein folds.
What is the folding funnel?
This type of structure is most commonly used as a host in guest host interactions.
What is a macrocycle?
The time that passes before fibrils start to appear in a fibrillation experiment.
What is the lag time?
The name of the protein that forms amyloid in E. coli.
What is CsgA?
This type of bond formation is commonly used to synthesize covalent cages.
What is dynamic bond formation?
The structural motif by which proteins forms fibrils (amyloid).
What is cross-beta?
A technique to identify hydrogen-bonded regions in a protein.
What is hydrogen exchange?
This common dynamic bond easily hydrolyzes in water.
What are imine bonds?
The sulfated carbohydrate polymer used to stimulate some proteins to aggregate.
What is heparin?
A bioinformatics approach to obtain structural information from related sequences.
What is residue co-evolution?
Most supramolecular or macromolecular structures are this type of product.
What is a thermodynamic product?
A solvent used to dissolve functional amyloid.
What is formic acid?
The protein that can be fused with CsgA to form underwater glue.
What is Mfp3 or Mfp5?
This determines the shape of covalent cages.
What are the angles between the bonding pieces (corner and linker)?