DCN
Developmental Genetics
Prenatal Brain Development
Brain Plasticity
Adolescence
100

A scientific debate between whether development is largely determined by innate predispositions or by experience

Nature vs. nurture

100

Forms of the same gene seen on a pair of chromosomes

Alleles

100

Folding of the neural plate in development of the neural tube

Neuralation

100

Specific period of development when certain input is required or typical development will not be observed

Critical period

100

This may mark the onset of developmental brain changes associated with adolescence

Puberty

200

Developmental changes in the brain that are expected to be due to aspects of the environment that are shared by all or most members of the species

Experience-expectant

200

This gene is affected in fragile X syndrome, and is expected to contribute to widespread effects, including autism-like symptoms

FMR1

200

This determines a neuron’s final position in the cortex when migrating with radial glia

Birthday

200

Within the maturational perspective, changes in levels of these may cause the end of sensitive periods

Neurotransmitters

200

Area of the brain implicated in impulsive behavior in adolescence

Prefrontal cortex

300

Founder of the constructivist view of child development

Jean Piaget

300

Many genes can play multiple roles at different times of development and in different areas of the developing individual because they are

Pleiotropic

300

This portion of the neural tube develops into the sensory cortex

Dorsal

300

According to the interactive specialization perspective, this process leads to the closure of sensitive periods

Specialization/differentiation

300

Network including the nucleus accumbens, found to be more active in adolescents than children and adults

Reward network

400

This viewpoint on human functional brain development holds that cognitive change is the result of ongoing interactions between brain development and experience-driven activation

Interactive specialization

400

Phenylketonuria causes intellectual impairment, at least in part through its effect on this neurotransmitter system

Dopamine

400

Neurons compete for these chemicals to ensure their survival

Neurotrophic factors

400

Prior experience making a brain region non-optimal for new learning

Entrenchment

400

Research from this perspective seeks to understand the many factors contributing to individual differences in adolescent brain development

Constructivist

500

At their extreme, perspectives emphasizing nature or nurture may be considered

Predeterminant/preformationist

500

A knockout mouse model of FXS has been used to show that the impacted gene is associated with learning but not ____

Fear conditioning 

500

Postnatal brain imaging work with preterm infants indicates that these first develop during the prenatal period

Resting state networks

500

The presence of this may increase awareness of plasticity in adulthood

Instability in the developmental system

500

Function within this brain region indicates that females may develop a more mature “social brain” earlier in adolescence

Amygdala