Depression
What SSRI is most likely to cause drowsiness and which is most likely to cause insomnia?
Fluoxetine = insomnia
Paroxetine = drowsiness
Why does Clozapine have a BBW?
Agranulocytosis or Neutropenia
What cardiovascular medication can be used to treat tremors from lithium therapy?
Propranolol
What two neurotransmitters play the biggest role in ADHD?
Dopamine and Norepinephrine
What is the mechanism of action of benzodiazepines?
Enhance GABA by modulating GABAa channels
What class of antidepressants has the highest risk of overdose?
Tricyclics
Why atypical AP should be taken with at least 350 calories to help with proper absorption?
Lurasidone (Latuda)
What are two dietary counseling points should you make with a patient taking lithium?
What ADHD medication is most notorious for the ghost tablet?
Methylphenidate (Concerta)
What antidepressant can be used if sexual dysfunction is experience with a different antidepressant?
Bupropion
Paliperidone and Risperidone
What are the two APs with indications for bipolar depression?
Lurasidone and Quetiapine
What medication class is first line in treating ADHD?
Stimulants
What three benzodiazepines are not metabolized in the liver?
Oxazepam, Temazepam, Lorazepam
What SSRI has an indication for use in OCD?
Fluvoxamine
What AP has the lowest incidence of EPS?
Mania impairs activities of daily living and lasts for more than 7 days; hypomania is less severe but lasts for at least 4 days
What prescription medications are most commonly added on to help with sleep for those with ADHD?
Clonidine and Guanfacine
What benzodiazepine forms the most metabolites?
Diazepam
What are three ways you can augment antidepressant therapy to help with resistant depression?
Atypical APs, Buspirone, or Anticonvulsants, etc.
What was the fist drug approved for treatment of tardive dyskinesias?
Ingrezza (valbenazine)
What is the difference between BP-I and BP-II?
Bipolar I means the patient has experienced a manic episode at least once
What amino acid is added to dextroamphetamine in Vyvanse to prevent abuse?
L-lysine
What medications primarily used for nerve pain has recently shown benefit in anxiety?
Lyrica and gabapentin