Lithium
OTHER mood stabilizers
GENERICS
and TRADES
Antiparkinson
Alzheimer's
100

Lithium MOA

Inhibit dopamine and glutamate and promotes GABA-mediated neurotransmision

100

Risperdal causes.....

Increased galactorrhea and amenorrhea 
100

lamotrigine

Lamictal

100

What three medications are used to treat EPS?

1. benztropine (Cogentin)

2. trihexyphenidyl (Artane)

3. diphenhydramine (Benadryl)

100

T/F - When a pt is on alzheimer medication c/o n/v/d you should discontinue the medicaiton.

FALSE. Titrate dose to reduce GI effects

200

Lithium USES

- mood swings

- mania

- antisuicidal 

- neuroprotective

200

Medication adverse effect includes: weight loss and mental dulling

topiramate (Topamax)
200
Trileptal 

oxcarbazepine

200

What three Extrapyramidal symptoms are relieved by antiparkinson medication?

Dystonia, Akathisia, Parkinsonism 

200

Taking donepezil (Aricept) and rivastigmine (Exelon) with concurrent NSAIDs use puts the patient at risk for what?

GI BLEED

300

What are the common side effects of Lithium?

nausea, fine tremors, increased thirst, polyuria, weight gain

300

What medication causes Stevens Johnson syndrome?

lamotrigine (Lamictal)

300

asenapine

Saphris

300

This medication is used to treat NMS by "Promoting dopamine"

bromocriptine (Parlodel)

300

Which medication is approved for moderate to severe stages of alzheimer?

memantine (Namenda)

400

Signs of lithium toxicity 

confusion, blurred vision, diarrhea, tinnitus, coma, convulsion 

400

Depakote therapeutic range and toxicity level 

Therapeutic range :50-125

Toxic: >150

400

cariprazine

Vraylar

400

These two medications help with eye blinking and grimacing, striking tongue out, jerking hand and leg movements manifestations of a condition known as Tardive Dyskinesia.

valbenazine (Ingrezza)

deutetrabenazine (Austedo)

400

What past medical hx should you be aware of when administering Aricept and Exelon for the risk of causing bronchoconstriction?

Asthma and COPD

500

Lithium therapeutic range + Toxicity levels

Therapeutic: 0.6 - 1.2

MILD: 1.5 - 2

MODERATE: 2-3

SEVERE: >3

500

What two things does Tegretol cause and at what level do you D/C?

1. Agranulocytosis

2. aplastic anemia 

3. ANC <1000

500

Caplyta

lumateperone

500

This medication inhibits calcium release from the sarcoplasmic reticulum helping symptoms of neuroleptic malignant syndrome like muscle rigidity.

dantrolene / Dantrium

500

What three medication subgroups are contraindicated with Aricept and Elexon for the risk of reducing therapeutic effects?

TCAs, FGAs, antihistamines