Addiction Psychiatry
PCLS
Anti-Psychotics
Neurotransmitters
Psych In the Cinema
100

This medication reduces alcohol cravings by interfering with glutamate neurotransmission and is often preferred in patients with liver disease.

What is Acamprosate?

100

This condition is considered the most common psychiatric syndrome encountered among hospitalized patients.

What is delirium?

100

A patient develops galactorrhea after risperidone because dopamine blockade occurred in this pathway.

What is the tuberoinfundibular pathway?

100

This neurotransmitter is primarily synthesized in the Locus Coeruleus.

What is Norepinephrine?

100

This film features a psychiatrist treating a child who famously reports, “I see dead people.”

What is The Sixth Sense?

200

This opioid‑use‑disorder medication can precipitate withdrawal if started too soon after full‑agonist opioids because of its high receptor affinity.

What is buprenorphine?

200

This endocrine disorder can masquerade as depression, with fatigue, slowed thinking, weight gain, and low mood.

What is hypothyroidism?

200

This atypical antipsychotic has high D4 affinity and minimal EPS risk.

What is the Clozapine?

200

Most of the brain's Serotonin is produced in these nuclei located in the brainstem.

What are the Raphe Nuclei?

200

This film portrays a Nobel Prize-winning mathematician with schizophrenia who experiences complex visual and auditory hallucinations.

What is A Beautiful Mind?

300

Chronic alcohol exposure causes compensatory upregulation of this excitatory receptor system, contributing to withdrawal seizures and autonomic instability during cessation.

What is the NMDA receptor system?

300

An EEG in a young patient with psychosis, seizures, dyskinesias, autonomic instability, and ovarian teratoma demonstrates this characteristic pattern strongly associated with anti-NMDA receptor encephalitis.

 What is extreme delta brush?

300

This second-generation antipsychotic is available in both oral and long-acting injectable formulations and is notable for causing significant hyperprolactinemia.

What is the risperidone?

300

Zofran is highly antagonistic at which serotonin receptor to prevent nausea and vomiting.

What is the 5-HT3 receptor?

300

In Silver Linings Playbook, Pat Solitano most clearly carries this DSM diagnosis.

What is bipolar I disorder?

400

A patient with severe alcohol use disorder develops confusion, horizontal nystagmus, gait instability, confabulation, and mammillary body damage involving disruption of this memory-related circuit.

What is the Papez Circuit?

400

Compared with neuroleptic malignant syndrome, serotonin syndrome is more likely to demonstrate this neuromuscular finding on examination.

What is hyperreflexia (clonus)?

400

This antipsychotic carries a uniquely high risk of QTc prolongation among second-generation agents and requires particularly cautious cardiac monitoring.

What is ziprasidone?

400

Olanzapine-associated weight gain is partly mediated through antagonism of this serotonin receptor.

5HT-2C

400

In this movie, Leonard Shelby’s profound inability to form new memories after trauma most closely resembles this neuropsychological condition. (Name the condition and the movie for full points)

What is anterograde amnesia and Memento?

500

A patient stabilized on methadone develops withdrawal symptoms after initiation of rifampin because this hepatic enzyme system was induced.

What is CYP3A4?

500

A patient with cirrhosis develops confusion and asterixis. Astrocytic conversion of ammonia into this compound contributes to cerebral edema in hepatic encephalopathy.

Glutamine

500

This percent receptor occupancy threshold is classically associated with emergence of extrapyramidal symptoms during antipsychotic treatment.

What is 80%?

500

Name BOTH synonymous terms for the neuropeptide neurotransmitter, produced in the lateral hypothalamus, that play a critical role in promoting wakefulness, arousal, and appetite 

What are orexin and hypocretin?

500

In this Pixar short often used in autism and neurodiversity teaching, a nonverbal autistic girl communicates through dance and movement with her camp buddy.

What is Loop?