Schizophrenia
symptoms of schizophrenia result from overactivity of dopamine system, specifically D2 receptors
What is dopamine hypothesis?
its MOA is to block only D2 receptors
What is first generation antipsychotics?
episodes of major depression and hypomania
What is bipolar disorder II?
first line treatment for depressive disorders?
What is SSRIs?
symptoms must last at least ___ to be diagnosed with general anxiety disorder
What is 6 months?
Flat affect, avolition, alogia, anhedonia, apathy/asociality
What are negative symptoms?
First generation antipsychotic that can cause QT prolongation
What is Haloperidol (Haldol)?
episodes of major depression and mania
What is bipolar disorder I?
Hypertensive crisis can occur with co-administration of these drugs and tyramine
What are MAOIs?
short-term only treatment for GAD
What is benzodiazepine?
Hallucinations, Delusions, Disorganized speech and behaviors
What are positive symptoms?
Have higher risk of extrapyramidal symptoms
What are first generation antipsychotics?
What is lithium?
Has the shortest half-life of all SSRIs
What is Paroxetine (Paxil)?
Fear of or anxiety regarding places from which escape might be difficult
What is agoraphobia?
most common hallucinations
What are auditory hallucinations?
Has a black box warning for agranolucytosis
What is clozapine?
What is lamotrigine?
Has the longest half-life of all SSRIs
What is fluoxetine (Prozac)?
Marked, persisting fear or anxiety of situations in which embarrassment can occur
What is social phobia?
the leading cause of premature death among schizophrenic patients
What is suicidal thoughts/suicide?
Most “typical acting” atypical
What is Risperidone?
Four episodes (manic or depressive) within a 12 month period
What is rapid cycling?
safe for pregnancy and breastfeeding (3 drugs)
What are citalopram, escitalopram, sertraline?
Most effective treatment of agoraphobia besides pharmacotherapy
What is cognitive-behavioral therapy?