General Facts
The three conditionals for diagnosis of AD excluding neurocognitive deficits.
What is:
significant interference with daily functioning, absence of delirium, and no other medical diagnostics.
Percentage of dementia caused by AD
What is between 60-70%?
The 4 domains of potential mechanisms for institutionalized worsening of AD.
What are physical, social, psychological, environmental?
Average age of onset?
What is 65 years?
Three greatest risk factors for AD development.
What are age, genetics and lifestyle
Number of people affected by dementia in 2013.
What are 55 million people?
The two effects that may explain neurocognitive decline in nursing home residents
What are selection and institutionalization effects?
Core feature of Alzheimer's Disease.
What is amnestic presentation (deficits in memory and learning)?
The condition for mild neurocognitive disease to be labelled as probable.
What is a family history of AD gene mutation?
Percentage of dementia cases in institutions due to reversible causes.
Two strongest predictors for placement in a nursing home.
!DOUBLE JEOPARDY!
What is a dementia diagnosis and low self-rated health status (2 to 6x fold increase)
The 6 cognitive domains relevant in NCD
(AND the first and last to be impacted for bonus points)
What are:
Learning and memory, executive function, complex attention, language, perceptual-motor and social cognition.
(Learning and memory first, social cognition last)
Increase in the probability of developing AD over time after age 65.
What is doubled after every 5 years?
The two proteins most commonly involved in molecular AD pathogenesis.
What are beta-amyloid peptide and tau proteins?
Percentage of people who develop early onset AD
What is 2%?
What is 38% decrease in dementia risk?