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Anxiolytics
Mood Stabilizers
Typical Antidepressants
Atypical Antidepressants
Antipsychotics
100
MOA
What is reduce overactivity of the CNS?
100
potentiate serotonin; drug of choice for bipolar mania
What is Lithium?
100
blocks the reuptake of neurotransmitters causing accumulation at the nerve endings; used for depression
What is TCA's (Amytriptyline)?
100
first line drug; inhibit serotonin reuptake; for depression, OCD, and panic disorders
What is SSRI's (Prozac, Lexapro, Zoloft)?
100
work only on positive symptom control; block dopamine receptors; used for bipolar disorder, schizophrenia, tourettes; commonly result in EPS.
What is Typical Antipsychotics (Haldol, Thorazine)
200
indications
What is anxiety, insomnia, to cause sedation, adjuncts in anesthesia
200
causes toxicity
what is low Na decreases lithium excretion?
200
second line treatment; inhibits enzyme in the CNS; higher levels or neurotransmitters in the brain; used for depression
What is MAOIs?
200
inhibit serotonin and norepinephrine; for depression, OCD, and panic disorders
What is SNRI's (Cymbalta, Effexor)?
200
Work on both negative and positive symptoms; block dopamine and serotonin receptors; less EPS and anticholinergic effects.
What is Atypical Antipsychotics (Rispedal, Clozaril, Abilify)?
300
Adverse Reactions
What is respiratory depression, sedation, drowsiness, amnesia?
300
N/V/D, thirst, polyuria, lethargy, slurred speech, muscle weakness, fine hand tremors
What is Early toxicity (<1.5)
300
Tyramine containing foods
What is coffee, cream, chinese food, yogurt, aged meats, red wine, yeast, avocados, fava beans, smoked/pickled meats, aged/mature cheeses?
300
inhibits uptake of dopamine, serotonin, and norepinephrine; for depression and smoking cessation
What is wellbutrin?
300
Involuntary contractions of oral and facial muscles, wavelike movement of extremities, occurs with continuous, long term antipsychotic therapy
What is Tardive Dyskinesia?
400
Common Drugs
What is Xanax, Valium, Ativan, Klonopin, Librium?
400
Course hand tremor, persistent GI upset, mental confusion, muscle hyperirritability, EEG changes, incoordination, sedation
What is Advanced Toxicity (1.5-2.0)?
400
charcoal slows the absorption; high mortality rate with overdose; can be addictive-no antidote
What is TCA's?
400
for major depressive disorder; potentiates effects of norepinephrine and serotonin
What is Remeron?
400
Altered mental status, seizures, muscle rigidity, sudden high fever, BP fluctuations, tachycardia
What is Neuroleptic Malignant Syndrome?
500
Antidote
What is Flumazenil (Romazicon)
500
Therapeutic Range of Lithium
What is 0.4-1.0?
500
Tyramine foods and MAOI's
What is hypertensive crisis-->cerebral hemorrhage, stroke, coma, death?
500
alters effects of serotonin in the CNS; for major depression
What is Trazodone?
500
Muscle spasms of face, tongue, neck, and back; facial grimacing, involuntary upward eye movements, laryngeal spasms
What is Acute Dystonia?