In Generation 1, you might as well just buy a car instead of this million-Pokedollar key item.
Bicycle

"The mystic combination!"
Tate & Liza
Stone Axe
This building was written out of the series due to it introducing gambling to kids.
Game Corner
A certain toilet-shaped bird may cause nearby Rainfall.
Drizzle
This cute item is used to water plants in Hoenn.
Wailmer Pail
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"The Barefoot Fighting Genius!"
Maylene
This move replaces Heart Swap, and Manaphy isn't here for a fair trade this time.
Take Heart
The original "Misty's Tears" card showed Misty without this.
Clothes
You won't want to hear a performance from a Pokemon with Moist Voice.
Liquid Voice
This item reveals the true forms of the Forces of Nature.
Reveal Glass

"The silent boy of mystery!"
Allister (bonus: his name in Japanese is Onion)
This multi-tool of a move has a high crit chance and can inflict poison, drowsiness, or paralysis.
Dire Claw
In Pokemon Gold and Silver, the ANGLER trainer class was censored outside of Japan because of this.
He was smoking a cigarette
Who knew that an Obsessed Gorilla could pack such a punch?
Gorilla Tactics
This Generation 7 key item is the only time a gym badge can be found inside of your bag.
Surge Badge

"The Incredibly Pretty Girl"
Whitney
This move replaces Power Trick.
Power Shift
A card featuring this fire-type Pokemon was altered due to the Pokemon pointing a weapon directly at the player.

Forgive my Pokemon for playing tricks, he just has a Teasing Heart.
Prankster
In Generation 5, this lost handkerchief can be returned to its owner on a Thursday.
Grubby Hanky

"The Spartan Mayor"
Drayden
This move's effect depend on the same variable as Tyrogue's evolution.
Mystical Power
The episode "The Kangaskhan Kid" of the Pokemon anime was censored because Tommy asked Misty this.
He asked if he could drink milk from her breasts
Poisoning your opponent is such an Underhanded Trick.
Poison Touch