Weird and Wonderful
What is a common cause of COPD in a young patient with no smoking history?
A1-Antitrypsin Disease
What paraneoplastic syndrome do we need to think of in individuals with Squamous Cell Carcinoma?
Para-thyroid related peptide causing increase PTH receptor activity and hypercalcemia
Long-term therapy with _________ reduces COPD exacerbations in one year.
Azithromycin/ erythromycin
What are 3 possible complications of thoracentesis?
1. Pneuomothorax
2. Re-expansion Pulmonary Edema
3. Hemothorax
What labs do you need to calculate the 3 components of Light's Criteria (4)?
1. Fluid Protein
2. Serum Protein
3. Fluid LDH
4. Serum LDH
True or False: Regular treatment with ICS increases the risk of pneumonia in COPD patient, especially in those with severe disease.
true
Name 3 Pulmonary conditions that are associated with Erythema Nodosum?
Tuberculosis, Histoplasmosis, Coccidiomycosis, Sarcoidosis, Psittacosis
(or others not mentioned acceptable if can be verified)
This NSCLC lung cancer subtype is typically located peripherally in the lung and is the most common cause of malignant pleural effusion.
NSCLC Adenocarcinoma
Name 3 possible intrathoracic causes of chronic cough.
COPD, Bronchiectasis, Left heart failure, TB, Lung cancer, Asthma, CF, Interstitial Lung disease, idiopathic cough
Name 3 Pulmonary Manifestations associated with Rheumatoid Arthritis/Treatment of RA?
Interstitial lung disease
Airways disease
Follicular bronchiolitis
Constrictive bronchiolitis (obliterative bronchiolitis)
Bronchiectasis
Cricoarytenoid arthritis
Rheumatoid nodules
Pleuritis
Inflammatory Pleural effusion
Vascular disease
Pulmonary hypertension
Vasculitis
Rheumatoid pneumoconiosis (Caplan syndrome)
Drug toxicity
(other answers acceptable if can be verified)
What are the 30 day and 1 year mortality rates for individuals presenting for lung cancer with malignant pleural effusion?
a) 30 day = 11%, 1 year = 48%
b) 30 day = 22%, 1 year = 74%
b) 30 day = 33%, 1 year = 52%
b) 30 day = 44%, 1 year = 90%
B
When we should avoid adding ICS to LABA?
repeated pneumonia events, blood eosinophils < 100cells/, history of mycobacterial infection
What are the 3 diagnostic criteria for ARDS as per the Berlin criteria?
1. Timing within 1 week of clinical insult of new/worsening sxs
2. CXR shows bilateral opacities not fully explained by effusions, lobar /lung collapse or nodules
3. Resp failure not fully explained by cardiac failure/fluid overload
For adenocarcinoma of the lung, what Staging typically indicates a limited invasive tumor or limited nodal disease, and is more likely to be treated with surgical resection?
Stage 1-3A
(Stages 3b and 4 involve mediastinal, subcarinal, and/or contralateral nodes and metastatic disease. These stages are considered unresectable and are treated with chemoradiation)
Differential diagnosis for COPD patient with suspected exacerbation
Heart Failure, Pneumonia, PE