Anemia Basics
This term is measured during blood analysis and shows the percentage of blood that is made of RBCs.
What is hematocrit?
This acquired stem-cell disorder involves a PIG-A mutation and makes RBCs susceptible to complement-mediated lysis.
What is paroxysmal nocturnal hemoglobinuria (PNH)?
Deficiency is this specific enzyme may cause hemolytic anemia.
What is G6PD?
This is a chronic myeloproliferative disorder chracterized by increased blood cell mass (erythrocytosis).
What is polyceythemia vera?
All ocular signs and symptoms can be attributed to…
This type of cell is the precursor to a RBC and contains no nucleus.
What is a reticulocyte?
This type of anemia results from vitamin B12 or folate deficiency.
What is megaloblastic anemia?
This condition is caused by abnormality in the RBC membrane protein spectrin.
Increased platelet production was given this term.
This is the term for the sign observed in polycythemia where a patient experiences burning pains in the distal extremities.
What is erythromelalgia?
These are the three mechanisms by which anemia may be caused.
What are decreased RBC production, increased RBC destruction, and blood loss?
A patient has macrocytic anemia, hyper-segmented neutrophils, and neurologic symptoms. This patient most likely has this type of anemia.
What is megaloblastic anemia?
Vitamin B12 deficiency causes neurologic deficits.
This type of hemolytic anemia involves this specific antibody reacting against the body’s own tissues.
What is cold autoimmune hemolytic anemia (AIHA).
Name one of the primary conditions causing excess RBC production.
What is polycthemia rebra vera OR primary erythrocytosis?
Typically, autoimmune hemolytic anemias are treated with this specific drug.
What is prednisone?
These are the MCV values that define microcytic, normocytic, and macrocytic anemias, respectively.
What is <80fl, 80-100fl, and >100fl ?
A patient with microcytic (iron deficient) anemia would show these levels of iron, transferrin, and ferritinin their blood analysis. (low, high, normal, etc).
Low iron, high transferrin, low ferritin.
More info:
low iron in the blood.
Transferrin is like the delivery truck (body sends more looking for iron).
Ferritin is like the warehouse for iron (empty).
This type of hemolytic anemia is caused by incompatibility between the Rh of the mother and fetus.
What is hemolytic disease of the newborn?
Also known as erythroblastosis fetalis
Renal carcinoma may cause this change to the amount of erythropoietin production.
What is increased erythropoietin production?
These are the vitamins crucial for RBC production.
(Folic acid was included in her slides under vitamins)
These two tests are important for the evaluation of anemia of chronic disease (ACD).
(hint: think about inflammatory markers)
What is ESR and CRP?
This type of RBC membrane defect shows altered distribution or proportion of membrane liquids as well as altered membrane protein or membrane skeleton abnormalities.
What is acanthocytosis?
Name one type of progenitor cell disorder
What is: pure red cell aplasia OR anemia of chronic disease OR anemia of chronic renal failure?