Respiratory Update

Reframing Asthma Care

100

Asthma is a ______ disease

Variable

200

Asthma patients are at risk of severe, potentially life threatening exacerbations, regardless of ________ _________

disease severity 

300

Using >_____ canisters of SABA a month is associated with an increased mortality?

a)  7

b)  3

c)  1

d)  5

b) 3

400

After 3 months, over 50% of patients have stopped maintenance therapy.  After a year adherence decreased to below____%

a)20%

b) 30%

c) 50%

d) 10%

20%

Symbicort and New Developments in Asthma

100

The SYGMA trials found a comparable risk of severe exacerbations with ____% lower inhaled corticosteroid load versus the traditional approach.

a) 75%

b) 50%

c) 25%

d) 60%

a) 75%

200

How long before an asthma attack are patients increasing their SABA use?

2 weeks

300

demonstrate how to correctly use the Symbicort turbuhaler.

Points awarded for correct demonstration.

400

How long does it take for Symbicort to begin to provide relief?

1-3 minutes

Diabetes Trials

100

In Declare, Forxiga reduces hospitalization of Heart Failure by

a) 12%

b) 18%

c) 22%

d) 27%

d) 27% (majority of patients in the trial are primary prevention)

200

What is the biggest Cardiovascular outcome trial done with T2D  patients?

a) EmpaReg

b) Declare

c) Canvas

b)  The Declare trial had as many patients as Canvas and EmpaReg combined

300

Forxiga is the most studied SGLT2 with evidence in the broadest group of patients of any SGLT2s and its totality of evidence spans the cardiorenal continuum. Can you name 3 landmark trials with Forxiga?

Declare, Dapa HF and Dapa CKD

400

What is the only drug indicated to provide cardiovascular protection in this patient?

PatientProfile:  A1C 8  / kidneys function / No signs of Cardiovascular disease / high blood pressure /

a) Januvia

b) Forxiga

c) Invokana

d) Jardiance

b) Forxiga - Based on the Declare trial that studied many primary prevention patients

Diabetes & Treatment

100

How many years does it take for 68% of patients with Type 2 Diabetes to show signs of left ventricular dysfunction?

a) 5 years

b) 8 years

c) 10 years

d) 15 years

a) 5 years. Cardiac changes occur very early in T2D patients - highlighting the importance of using a drug with proven cardiorenal protection in primary prevention patients

200

What percentage of Type 2 Diabetics in Canada are considered primary prevention patients

a) 50%

b) 60%

c) 75%

d) 82%

d) 82% 8/10 patients do not yet have established cardiovascular disease.

300

Which SGLT2 fixed dose combination  is the most prescribed in Canada?

Xigduo

400

What is the most prescribed SGLT2 by Canadian Cardiologists?

Forxiga