Retinochoroidal inflammation
Hereditary
Hereditary/Systemic Disease
Systemic Disease/Drug Induced
Vitreous and Fun Stuff
100
Three stages of VKH syndrome.
BONUS: Eponym for depigmentation of trabecular meshwork in VKH
1. Prodromal
2. Acute uveitic
3. Convalescent
BONUS: Ohno sign
100
What is the name of this hereditary disease and main symptom?
BONUS (+200): Gene?
Fundus albipunctatus, nyctalopia
BONUS: RDH5
100
The QB for the Cincinnati Bearcats, or a dystrophy. What is the gene?
Sorsby, TIMP3
100
Name 4 tests that can be used to screen for hydroxychloroquine toxicity?
BONUS (+100): Concomitant use of what drug increases toxicity? +200 for a common differential of toxicity from this drug that Hayden loved.
OCT Mac, HVF10-2 or 24-2, FAF, mfERG
BONUS: Tamoxifen, MacTel2
100
Gene for Stickler and orientation of lattice degeneration?
BONUS (+200):
How would you treat family members of a patient with this condition?
COL2A1, radial
BONUS: Laser to avascular retina
200
Posterior uveitis with electronegative ERG?
BONUS (+200): Infectious etiologies to consider in APMPPE and serpiginous, respectively.
Birdshot
BONUS: Syphilis, TB
200
Patient presents with this in the right eye. Left eye is normal. What is this called? Two possibilities.
BONUS (+300): If a patient has a history of uveitis in both eyes and presents to your clinic with fundus findings of RP, how can you tell whether it is post-inflammatory or true RP?
Pigmented paravenous retinopathy or sector RP
BONUS: ERG is extinguished in true RP but somewhat preserved in inflammatory causes
200
A young boy presents with a vitreous hemorrhage. What dystrophy must be on the differential and what is the ERG?
BONUS:
What disease? What is the fundus findings and what is the inheritance?
X-linked retinochisis, electronegative
BONUS: Stargardt, AR, pisciform flecks
200
Patient presents with decreased vision of unknown etiology. Clear PCIOL, no diabetic retinopathy, no glaucomatous cupping but noticeable pallor. Vessels are noticeably attenuated and OCT has outer retinal atrophy. What is the next step and what does the ERG show?
Systemic evaluation for cancer. Decreased or extinguished a- and b- waves.
200
List all stages of macular holes.
BONUS: Old drug used to treat VMT
See book
BONUS (+200): Verterporforin
300
How can you tell the difference between PAMM and AMN on OCT?
BONUS (+300): Neurosensory macular detachment after flu-like illness. What is it and what is prognosis?
PAMM involves INL and IPL hyperreflectivity, AMN presents with ONL and ellipsoid zone hyperreflectivity
BONUS: Acute idiopathic maculopathy, full recovery typically
300
What is the disease and ERG finding?
BONUS (+300): What color light sensitivity do they have. No steals and must get above right
Enhanced S-cone, Goldmann-Favre
BONUS: Blue
300
Name 4 disorders with pigmentary retinopathy and hearing loss?
BONUS (+500):
What is this called and what disease? +200 more for the enzyme it affects.
Alport, Alstrom, Cockayne, Rubella, MPS 1, Refsum
BONUS: Mizuo-Nakamura, Oguchi, arrestin
300
What is the cause of visual loss and what is the gold standard diagnosis?
BONUS: Two lethal forms of disease and what are the signs?
Foveal hypoplasia, VEP
BONUS: Chediak-Higashi -> Neutropenia
Hermansky-Pudlak -> Hemorrhaging Puerto Ricans
300
Who did Texas A&M beat this weekend? Clara and Chris can't answer
BONUS: What was the score?
Notre Dame
BONUS: 41-40
400
Vitreous cell pattern in PVRL, and how do you diagnose it?
BONUS: Two flow cytometry/gene rearrangement findings in PVRL. Be specific
String of pearls, vitrectomy with flow cytometry/gene rearrangement etc.
BONUS(+400): MYD88 and IL10/IL6 ratio >1.0
400
Disease, gene, and inheritance
BONUS: Closely related disease with OAT mutation and what is the treatment?
Choroideremia, CHM, X-linked
BONUS: Gyrate atrophy, arginine restriction and B6 supplementation
400
What disease that also has chorioretinal coloboma?
BONUS: Pigmentary retinopathy with cystic kidney disease and thoracic asphyxiating dystrophy?
Joubert
BONUS: Jeune
400
Child with pigmentary retinopathy, cerebellar ataxia, ployneuropathy, and hearing loss that has worsened. What does this patient need to stop ingesting?
BONUS: What is sea blue histiocyte syndrome?
Phytanic acid -> Refsum disease
BONUS: Neimann Pick type B
400
The phrase "my boy's wicked smaht" comes from what movei?
BONUS (+800): What subject is Matt Damon's girlfriend studying in the movie?
Good Will Hunting
BONUS: Organic chemistry
500
3 patterns of toxocariasis. Half credit for 2
BONUS: Infectious cause?
1. Peripheral granuloma with traction band
2. Posterior pole granuloma
3. Panuveitis mimicking endogenous endophthalmitis
BONUS: West Nile
500
Disease and explain how it it diagnosed? Be specific including finding of test.
BONUS:
Who would most likely have this dystrophy of people you know, assuming you did not know their visual acuity?
Best disease. AD. EOG with Arden ratio (Light/Dark trough) < 1.5
BONUS: Chris McMillan (North Carolina)
500
BONUS:
X-linked retinochisis, electronegative
500
What has the patient been exposed to?
BONUS (+500): 5 drug-induced causes of crystalline retinopathy
Pentosan polysulfate
BONUS: Canthaxanthine, ethylene glycol, Methoxyflurane, Nitrofurantoin, Talc emboli, Tamoxifen, Triamcinolone acetonide
500
Name 3 other branches of Dunder Mifflin besides Scranton.
BONUS (+500)
Holly is relocated to __1__
Karen becomes the manager of ___2__
The Scranton and ___3___ branches merge
Nashua (1), Stamford (3), Buffalo, Binghamton, Utica (2)