Antibody Positivity
This autoantibody is commonly associated with drug-induced lupus.
What is anti-histone
What is podagra
This condition is associated with proteinase 3 anti-neutrophil cytoplasmic antibody.
What is GPA
These are the 3 sequential colors classically associated with the color of the hand in Raynaud's phenomenon
What are white, blue, and red
What condition
Gout
This autoantibody is associated with congenital heart blocks.
What is anti-SSA/Ro (or SSB/La)
This type of crystal appears rhomboid-shaped and positively birefringent under polarized light.
What are calcium pyrophosphate crystals
This vasculitis involves large arteries and can present with a “pulseless” upper extremity, often in young women of Asian descent.
What is Takayasu arteritis
This is what CREST stands for
Calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia
What condition
Bamboo sign from axial spondylitis
This syndrome is associated with Jo-1 autoantibody.
What is antisynthetase syndrome
This blood pressure medication has a uricosuric effect.
What is losartan
This study on ANCA-associated vasculitis showed there were no significant differences in the outcomes between patients received PLEX versus those who did not.
What is the PEXIVAS trial
This is what differentiates between lcSSc and dcSSc
Patients with lcSSc has skin thickening only distal to the elbows/knees (+/- face/neck)
Name this sign and 3 other rashes associated with the condition
Gottron's papules.
Heliotrope rash, shawl sign, holter sign, V sign.
The percentage of patients with mixed connective tissue disease who have positive anti-RNP.
What is 100%
This study showed that febuxostat was non-inferior to allopurinol with regards to major cardiovascular events.
What is the FAST Trial (Febuxostat versus Allopurinol Streamlined Trial)
These are the 3 phases of eGPA
What are the prodromal (allergic) phase, the eosinophilic phase, and the vasculitic phase
THIS is the antibody associated with lcSSc, which is associated with THAT pulmonary complication.
THIS is anti-centromere Ab, and THAT is PAH.
Name the sign and associated condition
Strawberry gingivitis; GPA
This is last name of both a famous apple cultivator and a patient who helped researchers discover a highly specific autoantibody.
What is Smith
The mechanism of action of pegloticase
What is a recombinant uricase enzyme that converts uric acid into allantoin
This is the most common cause of irreversible blindness in GCA
What is Anterior Ischemic Optic Neuropathy (AION) (insufficient blood flow to the optic nerve head).
This score is used clinically to quantify skin involvement. (Bonus: describe how to calculate the score)
What is the modified Rodnan's skin score (mRSS)
This is the histopathology
Rheumatoid nodule