Site Specific
Most common form of skin cancer?
Basal cell carcinoma, Squamous cell carcinoma, Malignant melanoma?
Basal Cell Carcinoma
Anemia associated with Multiple Myeloma is related to?
Replacement of erythrocyte precursors with plasma cells. Can also be related to kidney failure.
Name the four fundamental ethical principles that guide medical decision making.
Autonomy, non-maleficence, Beneficence, and Justice
Which neutrophils mature into cells that migrate from the bloodstream into tissues the differentiate?
What 2 types of cells do they differentiate into while in the tissue.
Monocytes>>macrophages or dendritic cells
Why is leucovorin given with 5Fu?
To potentiate the antitumor effect of the chemo.
What chromosome diagnostic marker is most common in Chronic Myelogenous Leukemia?
Philadelphia chromosome
The cancer most associated with malignant ascites
Ovarian cancer
What is the best strategy to decrease risk for exposure to hazardous drugs?
PPE, and education on how to use it correctly.
Cancer cells can change ________________ to interfere with binding to antagonistic drugs.
target enzymes
What symptoms would you expect in early chemo induced Pulmonary toxicity?
Dyspnea, unproductive cough, bilateral basilar rales.
Multiple Myeloma is a cancer of what kind of cells?
Plasma Cells
Clinical manifestations of cancer in sigmoid colon
Abdominal pain and melena
What common occupational risks do Oncology nurses have.
Back and neck injuries.
Hazardous drug exposure.
What chemos are most known to cause hair loss?
Cyclophosphamide, doxorubicin, etoposide, irinotecan, paclitaxel, topotecan, vincristine.
What chemos are most likely to cause constipation and why?
Vinca alkaloids: Vincristine, Vinblastine, Vinorelbine. They can cause neuropathic issues in colon.
What is the most favorable prognostic factor in a patient with Small Cell Lung Cancer?
Female, normal LDH level, Good performance status, or Limited Stage disease.
Limited Stage at diagnosis
Most common metastatic site for Breast cancer
Bones.
Followed by Lung, liver, pleura, and brain.
What is the definition of Non-maleficence?
Obligation to do no harm.
The most common and lethal side effect of chemo is?
Myelosuppression
What is tumor angiogensis?
Process where tumors produce their own vascular network.
What would make a colorectal cancer prognosis poor?
High BP, Location of tumor above peritoneal reflection, Venous and Lymph node invasion, or Squamous cell involvement?
Venous and Lymph Node invasion
What types of cancers present with generalized itching?
Hodgkins Lymphoma and Non-Hodgkins Lymphoma, Multiple myeloma, and Small cell lung cancer.
What is it called when an adverse event with a patient causes death or serious injury?
Sentinel Event
What is the physiological cause of diarrhea in a chemo patient?
Microvilli flattening and reducing the absorptive surface.
What are the three distinct phases of hematopoiesis?
Proliferation, differentiation, maturation.