Name the antibody
This antibody is positive in GPA
c-ANCA (PR3)
Name the main antidote for organophosphate poisoning
Atropine
This is a common lung findings with SLE
shrinking lung syndrome
Absolute Risk Reduction (ARR) formula
ARR = CER (Control Event Rate) - EER (Exposed Event Rate)
Anion Gap
Na - HCO3 - Cl
This antibody is positive in drug-induced lupus
Anti-histone
What is the hallmark pH disruption from salicylate toxicity?
respiratory alkalosis and AGMA
At what PaO2 and what PaCO2 levels do you prescribe home oxygen?
PaO2 ≤55 (or 55-59 with cor pulmonale, pHTN, or Hct >55%)
PaCO2 ≥ 52
A systematic approach to making complex clinical or healthcare decisions by comparing the benefits, risks, and costs of different options. It uses tools like decision trees, probability models, and utility assessments to evaluate outcomes and guide decision-making under uncertainty.
Decision Analysis
Free water deficit
TBW x (Na - 140)/140
These 3 antibodies may be found in APLA
anti-cardiolipin, lupus anticoagulant, anti-B2 glycoprotein
Name 2 alcohols that will increase your osmolar gap but NOT your anion gap
isopropyl alcohol, ethanol
Patient has cirrhosis and ascites. They are on diuretics. 24hr urine Na is 85. How do you interpret this?
Are they losing weight or not? if the are, continue as is. if they are not - they are not compliant with Na restriction
Systematically developed recommendations designed to assist healthcare providers and patients in making decisions about appropriate care for specific clinical conditions or situations based on evidence from research and expert consensus.
Clinical Practice Guideline
Correct Na for hyperglycemia
Na (corrected) = Na (measured) + glucose/4
This antibody may be present in both limited cutaneous and diffuse cutaneous scleroderma
anti-RNA polymerase III
Skin in carbon monoxide is _____ coloured and in methemoglobinemia it’s ___ coloured
cherry red, slate grey
What do large v waves on JVP indicate?
TR
Calculation for positive predictive value
TP/(TP+FP)
Delta Delta with interpretation!
(12-AG) : (24-bicarb)
>2 is AGMA+metabolic alkalosis
= is pure AGMA
<0.8 is AGMA + NAGMA
These 2 dermatomyositis antibodies are associated with malignancy
anti-NXP2, anti-TIF1gamma
Name 3 indications for dialysis in salicylate toxicity
salicylate level >7.2, supplemental O2, aLOC, AKI, pH <7.2, coagulopathy, volume overload
Type I cryoglobulinemia vasculitis is associated with ____ and Type II/III is associated with _____
I: MPN (MGUS, MM, CLL, WM)
II/III: Hep C (also HIV, IE, Sjogren’s)
Calculation for sensitivity (form a 4x4)
TP/(TP+FN)
A-a gradient adjusted for regular atmospheric pressure
150-(PaCO2/0.8)-PaO2