Case Intox
Stages of Change
Medication
Neuro
Withdrawal
100

A 14 year old female is brought to the emergency room with elated mood, racing thoughts, restlessness and is noted to be sucking on a pacifer. Physical exam reveals tachycardia, hypertension, dilated pupils and tumors. Which drug is most likely responsible for her symptoms 

What is LSD

100
A youth has fallen back into his old behavior and getting behavioral reports for the exact things the he said he was going to change.
What is Relapse?
100

Reversal agent that causes complete antagonism on the GABA receptor complex 

What is Flumenzil 

100

this group of substances causes direct agonism of the serotonin (5-hydroxytryptamine [5-HT]) type 2A (5-HT2A) receptor

What are classical hallucinogens- psilocybin, LSD, mescaline and DMT

100

Withdrawal of these 3 substances can be lethal if left untreated 

What is Barbiturates, Alcohol and Benzos

200

a 24 year old man presents to the ED escorted by police. He is thrashing in his handcuffs and very agitated. On exam, he is hypertensive and has vertical nystagmus.. What substance did he use? 

What is Phencyclidine (PCP)

200
A youth is thinking about change, but have not made any plans or done anything yet.
What is Contemplation?
200

Option for patients with poor compliance and alcohol cravings 

What is Vivitrol 

200

potent inhibitor of neurotransmission mediated by NMDA receptors

What is PCP. 

200

Yawning, Perspiration, Runny Nose, Muscle Twitching 

What is Opioid Withdrawal 

300

A 40-year old presents to the ER with flushing, sedation and confusion. His vitals are BP 80/55, RR 12/min and pulse 60/min irregular pupillary constriction and poor coordination. What substance has this patient likely been using. 

What is Opioids?

300

A youth is making progress towards his change. He is in a good routine and has stopped receiving behavioral reports.

What is Maintenance?

300

Poorly absorbed, not metabolized by the liver and is excreted unchanged in urine. This makes it an effective choice for patients with hepatic insufficiency

What is Acamprosate - Campral

300

Inhibits update and Increases synaptic release of the monoamines- dopamine, serotonin, and norepinephrine

What is Amphetamines Vs. Cocaine- inhibits uptake 

300

Headache can be a hallmark symptom of withdrawal from this substance 

What is Caffeine 

400

Patient presents agitated and anxious. On physical exam he is slightly hypertensive and tachycardia. His pupils are dilated and he is perspiring. Utox is negative for cocaine. Which substance is most likely the cause of intoxication? 

What is Amphetamines? 

400
A youth is making plans and talking about how he is going to change.
What is Preparation?
400

Partial agonist of A4B2 and full agonist of A7  acetylcholine receptors

What is Chantix 

400

to increase GABA inhibitory effects this substances causes an increase in the ion channel duration

What are barbituates 

400

Increased appetite, anxiety, depressed mood, difficulty concentrating, insomnia, irritability, anger & restlessness 

What is Tobacco Withdrawal 

500
A 39 year old female presents with severe anxiety, palpitations, restlessness and irritability. She has no hx of those symptoms. B/P is 160/100, pulse is 115bpm and temperature is 98. Pupils are dilated. What condition explains her symptoms? 

What is Cocaine? 

500
List all five Stages of Change in order.
What is Pre-Contemplation, Contemplation, Preparation, Action, Maintenance, Relapse?
500

Used to inhibit the activity at the GABA receptor complex

What is Flumazenil

500

Mitragynine selective agonists of the opioid receptor type μ-opioid receptor.

What is Kratom

500

Irritability, Anxiety, Sleep disturbances, Depression. This substance stays in the system longer- so withdrawal may not be as intense. 

What is Cannabis withdrawal