A 14 year old female is brought to the emergency room with elated mood, racing thoughts, restlessness and is noted to be sucking on a pacifer. Physical exam reveals tachycardia, hypertension, dilated pupils and tumors. Which drug is most likely responsible for her symptoms
What is LSD
Reversal agent that causes complete antagonism on the GABA receptor complex
What is Flumenzil
this group of substances causes direct agonism of the serotonin (5-hydroxytryptamine [5-HT]) type 2A (5-HT2A) receptor
What are classical hallucinogens- psilocybin, LSD, mescaline and DMT
Withdrawal of these 3 substances can be lethal if left untreated
What is Barbiturates, Alcohol and Benzos
a 24 year old man presents to the ED escorted by police. He is thrashing in his handcuffs and very agitated. On exam, he is hypertensive and has vertical nystagmus.. What substance did he use?
What is Phencyclidine (PCP)
Option for patients with poor compliance and alcohol cravings
What is Vivitrol
potent inhibitor of neurotransmission mediated by NMDA receptors
What is PCP.
Yawning, Perspiration, Runny Nose, Muscle Twitching
What is Opioid Withdrawal
A 40-year old presents to the ER with flushing, sedation and confusion. His vitals are BP 80/55, RR 12/min and pulse 60/min irregular pupillary constriction and poor coordination. What substance has this patient likely been using.
What is Opioids?
A youth is making progress towards his change. He is in a good routine and has stopped receiving behavioral reports.
What is Maintenance?
Poorly absorbed, not metabolized by the liver and is excreted unchanged in urine. This makes it an effective choice for patients with hepatic insufficiency
What is Acamprosate - Campral
Inhibits update and Increases synaptic release of the monoamines- dopamine, serotonin, and norepinephrine
What is Amphetamines Vs. Cocaine- inhibits uptake
Headache can be a hallmark symptom of withdrawal from this substance
What is Caffeine
Patient presents agitated and anxious. On physical exam he is slightly hypertensive and tachycardia. His pupils are dilated and he is perspiring. Utox is negative for cocaine. Which substance is most likely the cause of intoxication?
What is Amphetamines?
Partial agonist of A4B2 and full agonist of A7 acetylcholine receptors
What is Chantix
to increase GABA inhibitory effects this substances causes an increase in the ion channel duration
What are barbituates
Increased appetite, anxiety, depressed mood, difficulty concentrating, insomnia, irritability, anger & restlessness
What is Tobacco Withdrawal
What is Cocaine?
Used to inhibit the activity at the GABA receptor complex
What is Flumazenil
Mitragynine selective agonists of the opioid receptor type μ-opioid receptor.
What is Kratom
Irritability, Anxiety, Sleep disturbances, Depression. This substance stays in the system longer- so withdrawal may not be as intense.
What is Cannabis withdrawal