Depression 101
What's in a name?
Counsel me
Safety & side effects
Clinical pearls
100

At least 5 of these symptoms must be present during the same two week period to be diagnosed with depression.

What is 

Energy - decreased
Sleep - increased/decreased
Concentration - decreased
Appetite - increased/decreased
Psychomotor agitation/retardation
Interest/pleasure - diminished
Suicidal ideation
Mood -depressed
Guilt or feelings of worthlessness

ESCAPISM G

100

This is the generic and brand name of an MAOI. 

What is Isocarboxazid [Marplan] or

 Phenelzine [Nardil] or 

Tranylcypromine [Parnate]

100

These types of food should be avoided with MAOIs because it can increase risk of hypertensive crisis/serotonin syndrome. 

What are tyramine-rich foods?

100

This SSRI is preferred for patients with cardiac risk.

What is sertraline?

100

This medication may be considered for patients requiring an antidepressant who also experiences generalized anxiety disorder, panic disorder or social anxiety. 

What is venlafaxine? 

200

The symptoms of serotonin syndrome. (At least 4)

What is Severe nausea, Dizziness, Headache, Diarrhea, Agitation, Tachycardia, Hallucinations or Muscle rigidity?

200

The 5 G's that increase bleeding risk when combined with SSRIs and SNRIs. (Natural products)

What is Garlic, Ginseng, Ginger, Ginkgo and Glucosamine?

200

These medications should be taken at bedtime to prevent daytime sedation.

What is paroxetine, mirtazapine and trazodone.
200

SSRIs when combined with MAOIs can increase the patient's risk of hypotensive crisis or serotonin syndrome and therefore requires a 2-week washout period. This medication is the one exception.

What is fluoxetine. 


Fluoxetine requires a 5 week washout period due to its long half-life.

200

This must be given with every antidepressant that is dispensed.

What is a MedGuide?

300
Natural products that may be used to treat depression.

What is St. John's wort, SAMe (S-adenosyl-L-methionine), 5-HTP (5-hydroxytryptophan) and Valerian?

300

This tertiary amine has a brand name formulation that is approved for insomnia. Bonus $50: What is the brand name?

What is doxepin? 


Bonus $50: Silenor

300

The time it takes for physical symptoms to improve after antidepressant use.

What is 1-2 weeks?

300

The warning regarding SSRI use during pregnancy?

What is persistent pulmonary hypertension of the newborn (PPHN)?
300

Usually prescribed to patients experiencing sexual dysfunction with traditional antidepressants.

What is bupropion or mirtazapine?

400

It is important to rule out these two conditions before starting antidepressant therapy.

What is Bipolar disorder & Anxiety

400

This SSRI/olanzapine combination product can be used for treatment-resistant depression. [Brand name?]

What is Symbyax?

400

This side effect may be heightened in some children, teenagers or young adults within the first few months of treatment or when the dose is changed.

What is an increase in suicidal thoughts or actions?

400

These side effects are present in SNRIs due to their affect on norepinephrine. 

What is increased heart rate, dilated pupils, dry mouth, excessive sweating and constipation? 

400

This medication is commonly used in oncology and skilled nursing facilities to help with sleep and increase appetite

What is mirtazapine?

500

Treatment with antidepressants should be done over this period of time before deemed that it is ineffective. 

What is 6-8 weeks?
500

This medication is also approved for treatment of peripheral neuropathy, fibromyalgia, GAD and chronic muscoskeletal pain.

What is duloxetine?

500

The max dose of escitalopram that can be taken per day in elderly to prevent risk of QT prolongation

What is 10 mg/day

500

These three drugs can cause metabolic issues including dyslipidemia, weight gain and diabetes.

What is aripiprazole, olanzapine and quetiapine?

500

These 3 SSRIs are also approved for Premenstrual Dysphoric Disorder (PMDD).

What is Fluoxetine, Paxil CR and Sertraline?