In the clinic
Abbreviated NAAA, this assay is the most common test for SARS CoV-2 infection
What is Nucleic Acid Amplification Assay?
This original name to describe the SARS CoV2 relied on early data for the emerging virus
What is nCoV2019?
This stage of vaccine development has cohorts of 20-100 people and tests for safety of different doses
What is Stage 1?
This percentage of people are thought to be responsible for 80% of COVID cases in so called superspreader events
What is 10 to 20%?
These antigen-specific cells persist in the body long after the initial infection for an augmented immune response on re-exposure
What are memory T cells?
This nucleotide analogue perturbs viral replication and was a candidate for treating SARS CoV-2 infection
What is remdesivir?
Typical for a Coronavirus, this is the length of the SARS CoV2 genome
What is 29,903?
Hepatitis B and shingles use this type of vaccine which is the most common type of vaccine in development for SARS CoV-2
What is protein subunit?
This value is defined as the number of expected cases directly generated by one case in a population
What is R0 or reproduction number?
This receptor in the innate immune response is expressed on sentinel cells such as macrophages and dendritic cells and is responsible for recognizing pathogen-associated molecules
What is toll-like receptor?
This minimally invasive procedure involves instillation of saline into a subsegment of the lung followed by suction and collection of the instillation
What is bronchoalveolar lavage or BAL?
This mutation gained widespread press coverage for its potential role in increasing infectivity, but many scientists are unconvinced
What is D614G?
This final phase of vaccine trials consists of government review and licensing application
What is regulatory review?
This timespan is defined as the duration between symptom onsets of successive cases in a transmission chain
What is the serial interval?
These specialized cells in the germinal centers undergo rapid cellular division and somatic hypermutation
What are centroblasts?
This cocktail drug for SARS CoV2 is produced in humanized mice after being identified in convalescent plasma
What is REGN-COV2?
This large open reading frame is cleaved into 16 non-structural proteins, including the RNA dependent RNA polymerase
What is ORF1ab?
Key to vaccine trials and the concept of lasting immunity, this term refers to measurable signs that a person or potential host is immune or protected against developing disease
What is correlates of immunity or correlates of protection?
This epidemiological chart has a row per case or exposure and lists demographic, clinical, or epidemiological information in the columns
What is a line list?
This fragment of immunoglobulin is responsible for the differences between IgG, IgA, IgM, IgD, and IgE classes
What is the Fc or fragment crystallizable?
This protein fragment is found in the blood as the result of clot breakdown and when elevated is a marker for coagulopathy in COVID 19
What is D-dimer?
At 1/2 the rate of influenza, this is the rate at which SARS CoV-2 mutates
What is 2 mutations per month?
Used by Gaston Ramon in developing tetanus and diphtheria vaccines, these were among the first adjuvants used for improved vaccine performance
What is breadcrumbs, tapioca, or starch?
This organization constitutes about 3,000 public health departments to gather and track the epidemiology of diseases in a community
What is the National Notifiable Diseases Surveillance System?
These secretory immune cells have characteristic cartwheel or clock face arrangement
What are plasma cells?