Dates
The paper " Peculiar elongated sickle shaped red blood corpuscles in severe case of anemia" Published
What is 1904?
The person who published their first findings on sickle cell anemia
Who is James B. Henrick?
This medication can help reduce the frequency of pain crises and the need for blood transfusions by stimulating the production of fetal hemoglobin, which reduces the sickling of red blood cells.
Hydroxyurea
Round seeds are dominant to wrinkled seeds. What would be the parent genotypes if you crossed a homozygous dominant with a homozygous recessive?
RR x rr
The first bone blood transfusion was performed as a treatment for sickle cell anemia.
What is 1960?
Which doctors discovered that the sickling shape of the hemoglobin was caused by a deterrent or lack of oxygen
Who are Dr. Pauling and Dr. Itano (+ others or wtv)
This is currently the only potential cure for sickle cell disease, but it's a complex procedure with risks. It's typically considered for patients with severe forms of the disease.
Stem cell transplant
Round seeds are dominant to wrinkled seeds. What percentage of the offspring will be round if you cross a parent who is homozygous dominant with a parent who is homozygous recessive?
100%
A National sickle cell anemia control act was passed
What is 1972?
The two scientists who discovered the trait as opposed to the gene
Who are doctors Hahn and Gillespie?
Regular transfusions can help reduce the risk of stroke and manage anemia by increasing the number of normal red blood cells in circulation.
Blood transfusion
Round seeds are dominant to wrinkled seeds. What would be the parent genotypes if you crossed a pure breeding round seeded plant with a plant that received different alleles from each parent?
RRxRr
The first FDA approved treatment for sickle cell anemia
What is Hydroxyurea?
The first successful treatment of SCA Using hydroxyurea was reported
What is Mid 1980's
A company invested in sickle cell research
The Red Cross Foundation
The sickling can be reversed with what element
Oxygen
Round seeds are dominant to wrinkled seeds. What would be the parent genotypes if you crossed two heterozygous plants?
Rr x Rr
The mutation causing sickle cell can be tied all the way back to one of the following 1910, 1600, 1748, 1948
What is over 1000 years ago?
The name of the 20 year old Grenadian man who Dr. Henrick based his study on
Who is Walter C. Noel?
What treatment manipulates dna
gene therapy
A homozygous round (dominant) seeded plant is crossed with a homozygous wrinkled seeded plant (recessive). What percentage of the offspring will also be homozygous?
0%
One of these can be used for small children a)Crizanlizumab b) Voxelotor c) myelosuppressive d)G-CSF e) None of the above
What is Voxelotor?
(Myelosuppressive in itself is not a medication)