Type I Hypersensitivity
Hives, hay fever, and asthma are example of...
What is: Localized Anaphylaxis
This type of mediation uses NK cells and macrophages to kill cells with antibody-antigen complexes.
This immune complex mediated reaction causes these symptoms when some of the antigen-IgG antibody complexes remain in circulation.
What is: clotting, complement system activation (inflammation), and the attraction of neutrophils
This delayed T cell-mediated reaction peaks in 2-3 days, causing...
What is: dermatitis, auto-immune diseases, tissue damage, and transplant rejection.
This antibody is the 1st respondent to infection and activates the complement system
What is: IgM
IgE is produced when the antigen bind to mucous membranes of Basophils or mast cells. Once bound, these cells release...
What is: histamine, prostaglandins, leukotrienes, and cytokines
The activation of inflammation, cell lysis, and macrophages is due to tissue damage caused by...
What is: Antibody-mediated cytotoxicity
The disseminated intravascular coagulation of small blood vessels
What is: clotting
This allergic contact reaction occurs when antigens bind to proteins on T cells, which release cytokines that attract macrophages.
What is: Dermatitis
This antibody is more effective, yet short-lived, residing in our mucus, breast milk, tears, and saliva.
What is: IgA
These types of localized anaphylaxis are ingested and inhaled, producing a wheal and flare rash, as well as causing an upper respiratory rhinitis, respectively.
What is: Hives and Hay Fever
Type II Hypersensitivity can result in either...
What is: transfusion reaction and Hemolytic Disease of Newborn.
Clotting can cause symptoms such as...
What is: a rash, joint pain, and pyelonephritis.
What is: cosmetics, poison ivy, poison oak, and nickel in metal jewelry.
This antibody releases histamine when bound to an allergen and protects against helminthes.
What is: IgE
This reaction can cause low BP, bronchi constriction, and organ failure due to the dilation of blood vessels by histamine and leukotrienes. Its effects can be treated with Epinephren.
What is: Systematic Anaphylaxis
When a donor's RBC is lysed by recipient's immune cells via IgM antibodies, causing low BP, pain, and nausea.
What is: Transfusion reaction
This reaction (formation of antigen-antibody complexes) can cause edema, pain, and necrosis of injection site, after receiving a Diphtheria or Tetanus toxoid vaccine
What is: arthus reaction
In this test, a protein from Mycobacterium tuberculin is injected into the skin. The antigen reacts with T cells, which release cytokines and increase number of macrophages in that region. What is this called?
What is: the Tuberculin Skin Test
This antibody coat bacteria to enhance phagoctytosis for long-term protection.
What is: IgG
This injection of anti-IgE antibodies to prevent the binding of IgE to Basophils or Mast Cells is used to treat asthma
What is: Immunotherapy
When a mother's anti-Rh antibodies (IgG) attack the RBC of a Rh positive fetus this is called...
What is: Hemolytic Disease of Newborn
This reaction can cause fever, hives, joint pain, kidney damage, and blood vessel inflammation, due to a reaction to serum proteins injected in Tetanus, Diphtheria, or Rabies vaccines
What is: Serum Sickness
A positive TB test results as...
What is: red, thickened skin in 1-2 days
This antibody produces defensins and activate basophils as a respiratory immune defense.
What is: IgD