Pathophysiology
Infection plus SIRS
What is Sepsis?
Everyone gets this to maintain sats > 93%.
What is Oxygen?
This substance is produced in response to bacterial infections and also in response to tissue injury. Usually undetectable in healthy states but rises in response to pro-inflammatory stimuli.
What is Procalcitonin?
These 3 types of infections are the most common causes of sepsis
What is pneumonia, UTI, and wounds/cellulitis?
Sepsis is Just this type of shock.
What is Distributive?
Infection plus 2 or more SIRS and at least 1 sign of organ dysfunction.
What is Severe Sepsis?
Lactate, blood cultures, and antibiotics must be done.
What is within 1 hour of recognition of sepsis symptoms?
An enzyme that prevents inappropriate clot formation.
What is activated protein C?
The use of this device increases a patient's risk for Urosepsis
What is a foley catheter?
Sepsis is Just SIRS plus this.
What is a documented or potential infection?
Lactate 4.0 or greater
What is Septic Shock?
The Gold Standard for initiating antibiotics and fluids
What is within one hour of severe sepsis time zero?
The GOLD STANDARD in diagnosis of Sepsis.
What are Blood Cultures?
These are 2 simple ways to decrease the risk of sepsis
What are hand hygiene and daily bathing?
There are Just two phases of severe sepsis. In this phase, the patient might have a MAP that is normal.
What is Early Severe Sepsis: Hyperdynamic Phase?
This is the number one organ failure found in sepsis
What is kidney failure?
You must remeasure the lactate how often if elevated?
What is every 3 hours x 3?
You will see decreased amounts of these sticky blood cells and and increased risk of bleeding as a result with DIC. - Look out RANDI!
What are platelets?
Organisms that have the potential to cause sepsis
What are bacteria, virus, and fungus?
In kids, this is Just the most common presenting symptom of SIRS.
What is a fever?
When glucose is metabolized without oxygen this acid is formed in sepsis, an indicator of hypoxia to the tissues.
What is lactic acid?
Drug of choice for refractory hypotension with a MAP < 65 mm Hg after fluid resuscitation in sepsis.
What is Norepinephrine?
This accompanies a lab report and let's us know if the antibiotic of choice is appropriate.
What is the culture and sensitivity report?
This type of infection frequently leads to an increase in Bilirubin
What is Cholangitis or Cholecystitis?
If the client in DIC has a deficiency of all coagulation factors and are actively bleeding, they Just may need a transfusion of this type of product.
What is FFP? FFP contains all the clotting factors, fibrinogen, albumin, electrolytes, anticoagulants like protein C and added anticoagulants. Platelets restore clotting factors and platelets only.