General
Infection + profound circulatory, cellular, and metabolic abnormalities that substantially increase mortality
Septic shock
Reason for A compromise
Drop in GCS
Sepsis of unknown origin, first line and normal eGFR
Co-amoxiclav 1.2g IV and gentamicin for first 48-72h and review adjust treatment as per sensitivities
Call this number
2222
Renal
The most common infection that precipitates sepsis
Pneumonia
Derangements in B: tachypnoea and ...
Sepsis of unknown origin, severe penicillin allergy
Gentamicin for first 48-72h and review adjust treatment as per sensitivities
Scale 2 sats
88-92%
Respiratory
ARDS
Frequency of observations
Every 30 mins
C compromise: over 3 seconds
Capillary refill time
Sepsis of unknown origin, previous or suspected MRSA positive
Add vancomycin to appropriate first/second/etc line (aim for pre-dose levels 15-20mg/L)
Hypoglycaemia
<4mmol/L
Cardiovascular
Heart failure
Moderate risk: urine output ...
Urine output=0 in last 12-18h
Disability derangement: eyes open to pain, groans only, extends to pain
GCS 6 (E2V2M2)
Septic shock
Meropenem 1g IV TDS and vancomycin (aim for pre-dose levels 15-20mg/L)
Increase in mortality by x for every hour's delay
7.6%
Hepatic encephalopathy
High risk category: SBP ...
SBP <90 or >40 below baseline
Last step in exposure
Flip the patient
Febrile neutropenia, first line and normal eGFR
Tazocin 4.5gIV QDS and amikacin 20mg/kg IV OD
Volume of NS
Haematological
DIC