Medications
Highest risk of medication class for serotonin syndrome when used with SSRIs, TCA's, etc.
What are MAOIs?
Foods high in ____ can cause serotonin syndrome when combined with high risk medications
What is tyramine?
Increases synaptic concentrations of serotonin by inhibiting reuptake
What is an SSRI?
Brand name of escitalopram
What is Lexapro?
Which is indicative of Serotonin Syndrome: bradycardia or tachycardia?
What is tachycardia?
MAO-I's should be held for ___ days prior to starting an SSRI
What is 14 days?
Type of alcohol which contains tyramine and often paired with pizza or pasta,
What is wine?
Alpha-2 receptor antagonist
What is mirtazapine?
Brand name of bupropion
What is Wellbutrin?
Which is indicative of Serotonin Syndrome: low BP or elevated BP?
What is elevated BP?
Drug class often used to treat pain which can cause increased serotonin levels
What are opioids?
The "aged" forms of this is often high in tyramine
inhibits reuptake of dopamine and norepinephrine
What is bupropion?
Brand name of duloxetine
What is Cymbalta?
Which is indicative of Serotonin Syndrome: altered mental status or coherent?
What is altered mental status?
Which antibiotic, that covers MRSA can cause serotonin syndrome when combined with other serotonergic medications?
What is linezolid?
Types of "cured" ____ often contain high amounts of tyramine
What are meats? (summer sausage, pepperoni, and salami)
What are Monoamine Oxidase Inhibitors?
Brand name of amitriptyline
What is Elavil?
Which is indicative of Serotonin Syndrome: diaphoresis or no diaphoresis?
What is diaphoresis?
Often used prior to imaging of an organ or Cath lab and can cause increased levels of serotonin
What is IV contrast dye (methylene blue)?
Often enjoyed as a sauce along with sushi and fish, however is high in tyramine due to fermentation process
What is soy sauce?
Inhibits reuptake of NE and Serotonin in the synaptic cleft, also act on numerous other receptors such as M1, H1, and Alpha-1
What are TCAs?
Brand name of mirtazapine
What is Remeron?
Which is indicative of Serotonin Syndrome: dilated pupils or constricted pupils?
What are dilated pupils?