Clinical Trials
Judith Hockman et Al published this in new England journal in 1999
what is SHOCK Trial
SCAI class A
what is "At Risk"
Failure of initial support strategy to restore perfusion as evidenced by worsening hemodynamics or rising lactate.
What is SCAI class D
This 2012 NEJM trial Randomized patients with acute MI and Cardiogenic shock to IABP vs standard of care
What is SHOCK II trial
SCAI class B
What is "Beginning"
Actual or Impending circulatory collapse
What is SCAI class E
This trial published in NEJM in 2021 compared use of dobutamine VS milrinone in patients with Cardiogenic shock
What is DOREMI trial
SCAI Class C
what is "classic"
A patient who manifests with hypoperfusion and who requires one intervention (pharmacological or mechanical) beyond volume resuscitation.
What is SCAI class C
Published in Circulation in 2019 this pilot trial used Impella CP to unload LV with a 30 minute delay to reperfusion of patients with Anterior STEMI
What is DTU STEMI pilot trial
SCAI class D
What is "deteriorating"
A patient who is not currently experiencing signs or symptoms of CS, but is at risk for its development
What is SCAI class A
Published in 2023 in Circulation, this trial compared strategy of early unloading patients on ECMO vs usual management with selective unloading when needed.
What is "EARLY UNLOAD"
SCAI class E
What is "extremis"
A patient who has clinical evidence of hemodynamic instability (including relative hypotension or tachycardia) without hypoperfusion.
What is SCAI class B