Trippin' through history
The town in Saskatchewan where the term "psychedelic" was coined.
What is Weyburn?
This is the primary receptor sub-type that psychedelics activate to cause hallucinations.
What is the 5HT2a receptor?
Name one symptom that mimics the effects of sympathetic nervous system activation that can be caused by several psychedelics.
What is: increased heart rate, increased blood pressure, increased body temperature, sweating.
This psychedelic compound is used clinically to treat motion sickness.
What is scopolamine?
The Swiss chemist who first synthesized LSD.
Who is Albert Hofmann?
The phrase the describes the selective activation of some downstream signalling pathways over others after receptor activation.
What is biased agonism?
The adverse effects experienced by some under the effects of LSD are referred to as this.
What is a "bad trip"?
This catecholaminergic psychedelic can be legally used by some groups in the US as part of religious ceremonies.
What is mescaline?
This is the more common street name for the drug often ingested at raves. At least, back when I was bangin' (a.k.a., the good ol' days).
What is ecstasy/"Molly"?
This is the active metabolite of psilocybin.
What is psilocin?
Of the psychedelics described last time in class, this compound required very low doses to produce visual hallucinations. Anything beyond this can cause severe symptoms like limb numbness and tremors.
What is LSD?
A major component of ayahuasca, this drug is also known as the "business man's LSD" due to its short onset/offset of action and its relatively mild hallucinogenic effects.
What is DMT?
Another name for April 19, a famous day in psychedelic circles.
What is Bicycle Day?
The physical property of serotonin that makes it lack psychedelic properties.
What is its membrane impermeability?
The term for psychedelic drugs and their synthetic derivatives that can increase the number of dendrites and dendritic spines.
What are psychoplastogens?
This compound is administered intravenously to treat the malignant hyperthermia that can occur in response to MDMA use.
What is dantrolene?
This is the street name for the non-serotonergic psychedelic drug that can result in violent behaviour with higher doses.
What is angel dust?