Microbes
This is the PAMP that you would see on a Gram-negative bacterium.
What is LPS?
For extra points, what is the PAMP you might see on Gram-positive bacterium?
Patients who lack this type of immunity are unable to control an infection at all (i.e. have no initial "barrier").
What is innate?
What lymphocyte has the most dark-staining granules?
A. Basophils
B. Eosinophils
C. Neutrophils
D. A, B, & C
E. None of the above
What is E?
This is the role of the complement system.
What is tagging pathogens for destruction or destroying pathogens by poking holes in the microbe?
This is the proportion of leukocytes from most to least abundant.
What is...
Neutrophils, lymphocytes, monocytes, eosinophils, basophils
These are the four types of pathogens.
What are bacteria, viruses, fungi, and parasites?
These are the major cells of the adaptive immune system.
What are B and T cells?
This is the precursor for B cells.
What is the common lymphoid precursor?
For extra points, determine the precursors for the following:
T cells, basophils, platelets
What is the main role of C5a?
A. Recruit basophils to site of infection
B. Recruit eosinophils to site of infection
C. Recruit neutrophils to site of infection
D. None of the above
What is C?
This is the role of Kupffer cells.
What are phagocytic cells of the liver?
This type of bacteria "eats at the same table" and is not harmful to the host.
What are commensal bacteria?
For extra points,
T or F: Commensal bacteria are resistant to antibiotics.
This is what happens when a foreign epitope is recognized by a lymphocyte during adaptive immune system.
What is clonal selection and clonal expansion?
This granulocyte is short-lived, dies at the site of infection, and is phagocytic.
What are neutrophils?
For extra points,
Neutrophils are pyogenic. What does this mean?
True or False: C3a and C5a are referred to as anaphylatoxins and contribute to acute inflammation.
What is true?
This is where hematopoiesis occurs.
What is the bone marrow?
This is what Edward Jenner used to create the first vaccine.
What is vaccinia (cowpox)?
For extra points, what was this used against?
This is how long it might take the primary immune response to take place.
What is 7 days?
This is the function of dendritic cells.
What is presenting peptide antigens to T cells?
For extra points, what is the role of FDCs?
What is the C3 convertase of the classical pathway?
A. C3bBb
B. C4b2a3b
C. C4b2a
D. C4bC3a
What is C?
This is the cytokine that ILC-2 and TH2 cells secrete.
What is IL-4 and IL-5?
For extra points, determine what NK, CD8, ILC1, TH1, ILC3, and TH17 secrete.
This is the ONLY eradicated human pathogen.
What is smallpox?
These are the characteristics of innate and adaptive immunity.
What is...
Innate- rapid response, fixed, limited # of specificities, and constant during response
Adaptive- slow response, variable, numerous highly selective specificities, and improve during response
What is the main difference between monocytes and macrophages?
A. Monocytes are phagocytic, whereas macrophages are not
B. Monocytes are located in the peripheral blood
C. Macrophages are located in tissues
D. A & B
E. B & C
What is E?
This is the order of activation for the complement system.
What is alternative, lectin, classical?
For extra points, why is the classical pathway the last to be activated?
T or F: All lymphocytes are leukocytes.
For extra points, are all cytokines chemokines?