Symptoms
Causes
treatment
Famous figures
general facts
100

What is a common sign of sickle cell disease that causes extreme tiredness?


Anemia – Extreme tiredness due to a shortage of red blood cells.

100

What gene mutation causes sickle cell disease?

HBB gene mutation – A genetic mutation that leads to sickle cell disease.

100

What medication is used to reduce pain crises in sickle cell patients?


Hydroxyurea – A medication used to reduce pain crises.

100

Which Grammy-winning TLC member has publicly spoken about her struggles with sickle cell disease?


Tionne "T-Boz" Watkins – Grammy-winning singer from TLC.

100

What shape do sickle cells take?

Sickle-shaped – Red blood cells take on a crescent shape instead of being round.

200

What painful event occurs when sickle cells block blood flow?

Pain crises – Episodes of severe pain caused by blocked blood flow.

200


What type of hemoglobin is abnormal in sickle cell disease?


Hemoglobin S – The abnormal type of hemoglobin responsible for sickle-shaped cells.

200

What procedure can be a potential cure but is not widely available?


Bone marrow transplant – A potential cure for sickle cell disease but not widely available.

200

Which legendary jazz musician lived with sickle cell disease?

Miles Davis – Legendary jazz musician.

200

How is sickle cell disease inherited?

Passed from parents – Inherited through an autosomal recessive pattern.

300


How does sickle cell disease affect the growth of children?


Delayed growth – Lack of oxygen slows development in children.

300

How is sickle cell disease passed from parents to children?

Autosomal recessive inheritance – The disease is passed down when a child inherits two copies of the mutated gene.

300

What treatment helps increase the number of normal red blood cells in patients?

Blood transfusions – Increase the number of normal red blood cells.

300


Which member of The Temptations battled sickle cell disease?


Paul Williams – Singer from The Temptations.

300

What ethnic groups are most affected by sickle cell disease?


Most common in African, Mediterranean, Middle Eastern, and Indian populations – More prevalent in these ethnic groups.

400

What problem can sickle cell disease cause in the eyes?

Vision problems – Blocked blood flow can damage the retina.

400


What does "autosomal recessive" mean in genetics?


Genetic inheritance – Sickle cell disease is inherited from parents.

400

What type of care helps prevent infections in sickle cell patients?

Preventive care – Vaccinations and antibiotics help prevent infections.

400

What NFL player has sickle cell trait?


Geno Atkins – NFL player.

400

Which organ is most affected by sickle cell disease?

Spleen – One of the most affected organs in sickle cell disease.

500


How does sickle cell disease affect the hands and feet?


Swelling – Hands and feet may swell due to circulation issues.

500

Can a person have only one copy of the sickle cell gene and still show symptoms?

Yes – A person with one copy of the gene has sickle cell trait and may show mild symptoms.

500

What lifestyle changes can help manage sickle cell disease?

Healthy lifestyle – Staying hydrated, avoiding extreme temperatures, and managing stress can help control symptoms.

500

Name one way famous individuals have raised awareness about sickle cell disease.

Raising awareness – Many public figures have spoken out, raised funds, or shared their experiences to educate others about the disease.

500

What month is National Sickle Cell Awareness Month?

September – National Sickle Cell Awareness Month.